Job title: Professor of Occupational and Environmental Health

Phone: +86-27-83657914

Email: ghuan5011@gmail.com; ghuan5011@mail.hust.edu.cn

Academic Areas: lung carcinogenesis

Research Interests:

1. Molecular epidemiology studies of genetic susceptibility and gene-environment interactions in lung carcinogenesis.

2. Biomarkers for early screening and exposure assessment of high risk populations of lung cancer.

3. Studies on the biological effects of occupational and environmental polycyclic aromatic hydrocarbons (PAHs) exposure and genetic damage of coke oven workers with the techniques of molecular and cellular biology, toxicology, and epidemiology.

Academic Degrees

2000/09-2005/06       Bachelor of Medicine in Preventive Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China

2005/09-2010/06       Ph.D. of Medicine in Occupational and Environmental Health, Mentor: Professor Tangchun Wu, Ministry of Education Key Lab for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology,  Wuhan, 430030, Hubei, China

2007/10-2008/12       Exchange student in Cancer Epidemiology and Etiology,  Mentor: Professor Dongxin Lin,  Cancer Institute (Hospital), Peking Union Medical College , Chinese Academy of Medical Sciences, Beijing, 100021, China

Professional Experience

2010.7 to 2012.11      Associate Professor, Dept. of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

2012.11 to 2013.11    Visiting Associate Professor, Division of Environmental Health Sciences, School of Public Health, Yale University

2013.11 to 2015.11     Associate Professor, Dept. of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

2015.11 to present     Professor, Dept. of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology

Selected Publications

Corresponding author publications:

1. Bai Y, Feng W, Wang S, Zhang X, Zhang W, He M, Zhang X, Wu T, Guo H*. The Essential Metals Zinc, Selenium, and Strontium Protect against Chromosome Damage Caused by Polycyclic Aromatic Hydrocarbons Exposure. Environ Sci Technol. 2016, 50(2):951-60. (T2, SCI Impact Factor: 5.33)

2. Wang T, Feng W, Kuang D, Deng Q, Zhang W, Wang S, He M, Zhang X, Wu T, Guo H*. The effects of heavy metals and their interactions with polycyclic aromatic hydrocarbons on the oxidative stress among coke-oven workers. Environ Res. 2015, 140: 405-413. (SCI Impact Factor: 4.373)

3. Dai X, He X, Zhou Z, Chen J, Wei S, Chen R, Yang B, Feng W, Shan A, Wu T, Guo H*. Short-term effects of air pollution on out-of-hospital cardiac arrest in Shenzhen, China. Int J Cardiol. 2015, 192:56-60. (SCI Impact Factor: 4.036)

4. Li X, Bai Y, Wang S, Nyamathira SM, Zhang X, Zhang W, Wang T, Deng Q, He M, Zhang X, Wu T, Guo H*. Association of body mass index with chromosome damage levels and lung cancer risk among males. Sci Rep. 2015, 5:9458. doi: 10.1038/srep09458. (SCI Impact Factor: 5.578)

5. Li X, Wei J, Xu P, Yin X, Hu D, Zhang X, Liu L, Zhang K, Zhou C, Wang T, Zhang X, He M, Wu T, Yang M, Guo H*. The interaction of APEX1 variant with polycyclic aromatic hydrocarbons on increasing chromosome damage and lung cancer risk among male Chinese. Mol Carcinog. 2015, 54 Suppl 1:E103-11. (SCI Impact Factor: 4.808)

6. Guo H*, Huang K, Zhang X, Zhang W, Guan L, Kuang D, Deng Q, Deng H, Zhang X, He M, Christiani D, Wu T. Women are more susceptible than men to oxidative stress and chromosome damage caused by polycyclic aromatic hydrocarbons exposure. Environ Mol Mutagen. 2014, 55(6):472-81. (SCI Impact Factor: 2.63)

7. Xin L, Wang J, Guo S, Wu Y, Li X, Deng H, Kuang D, Xiao W, Wu T, Guo H*. Organic extracts of coke oven emissions can induce genetic damage in metabolically competent HepG2 cells. Environ Toxicol Phar. 2014, 37(3):946-53. (SCI Impact Factor: 2.084)

8. Kuang D, Zhang W, Deng Q, Zhang X, Huang K, Guan L, Hu D, Wu T, Guo H*. Dose-response relationships of polycyclic aromatic hydrocarbons exposure and oxidative damage to DNA and lipid in coke oven workers. Environ Sci Technol. 2013, 47(13):7446-56. (SCI Impact Factor: 5.33)

9. Xu P, Liu L, Wang J, Zhang K, Hong X, Deng Q, Xiang J, Zhang X, He M, Wu T, Guo H*. Genetic variation in BCL2 3’-UTR was associated with lung cancer risk and prognosis in male Chinese population. PLoS One. 2013, 8(8):e72197. (SCI Impact Factor: 3.234)

First Author and co-first author Publications:

10. Liu C, Guo H*, Cheng X, Shao M, Wu C, Wang S, Li H, Wei L, Gao Y, Tan W, Cheng S, Wu T*, Yu D*, Lin D*. Exposure to airborne PM2.5 suppresses microRNA expression and deregulates target oncogenes that cause neoplastic transformation in NIH3T3 cells. Oncotarget. 2015 Oct 6;6(30):29428-39. (*Co-first author) (SCI Impact Factor: 6.359)

11. Guo H, Jin Y, Cheng Y, Leaderer B, Lin S, Holford TR, Qiu J, Zhang Y, Shi K, Zhu Y, Niu J, Bassig BA, Xu S, Zhang B, Li Y, Hu X, Chen Q, Zheng T. Prenatal exposure to organochlorine pesticides and infant birth weight in China. Chemosphere. 2014, 110:1-7. (SCI Impact Factor: 3.34)

12. Guo H, Bassig BA, Lan Q, Zhu Y, Zhang Y, Holford TR, Leaderer B, Boyle P, Qin Q, Zhu C, Li N, Rothman N, Zheng T. Polymorphisms in DNA repair genes, hair dye use, and the risk of non-Hodgkin lymphoma. Cancer Causes Control. 2014, 25(10):1261-70. (SCI Impact Factor: 2.735)

13. He M, Wu C, Xu J, Guo H*, Yang H, Zhang X, Sun J, Yu D, Zhou L, Peng T, He Y, Gao Y, Yuan J, Deng Q, Dai X, Tan A, Feng Y, Zhang H, Min X, Yang X, Zhu J, Zhai K, Chang J, Qin X, Tan W, Hu Y, Lang M, Tao S, Li Y, Li Y, Feng J, Li D, Kim ST, Zhang S, Zhang H, Zheng SL, Gui L, Wang Y, Wei S, Wang F, Fang W, Liang Y, Zhai Y, Chen W, Miao X, Zhou G, Hu FB, Lin D, Mo Z, Wu T. A genome wide association study of genetic loci that influence tumour biomarkers cancer antigen 19-9, carcinoembryonic antigen and α fetoprotein and their associations with cancer risk. Gut. 2014, 63(1): 143-51. (*Co-first author) (SCI Impact Factor: 14.66)

14. Deng Q, Guo H*, Dai J, Yang L, Wu C, Wang Q, Hu Z, Yang M, Liu L, Yu D, Hu D, Hong X, Qiu F, Yang H, Wang T, Tan W, Chu M, Feng J, Teng K, Gong J, Sun C, Hu X, Zhang K, Lu J, Lin D, Shen H, Wu T. Imputation-based association analyses identify new lung cancer susceptibility variants in CDK6 and SH3RF1 and their interactions with smoking in Chinese populations. Carcinogenesis. 2013, 34(9):2010-6. (*Co-first author) (SCI Impact Factor: 5.334)

15. Guo H, Deng Q, Wu C, Hu L, Wei S, Xu P, Kuang D, Liu L, Hu Z, Miao X, Dr. Shen H, Lin D, Wu T. Variations in HSPA1B at 6p21.3 are associated with lung cancer risk and prognosis in Chinese populations. Cancer Res. 2011, 71(24):7576-86. (SCI Impact Factor: 9.329)

16. Guo H, Bai Y, Xu P, Hu Z, Liu L, Wang F, Jin G, Wang F, Deng Q, Tu Y, Feng M, Lu D, Shen H, Wu T. Functional promoter -1271G>C variant of HSPB1 predicts lung cancer risk and survival. J Clin Oncol. 2010, 28(11):1928-35. (SCI Impact Factor: 18.428)

17. Yang M, Guo H*, Wu C, He Y, Yu D, Zhou L, Wang F, Xu J, Tan W, Wang G, Shen B, Yuan J, Wu T, Lin D. Functional FEN1 polymorphisms are associated with DNA damage levels and lung cancer risk. Hum Mutat. 2009, 30(9):1320-8. (*Co-first author) (SCI Impact Factor: 5.144)

18. He M, Guo H*, Yang X, Zhou L, Zhang X, Cheng L, Zeng H, Hu FB, Tanguay RM, Wu T. Functional SNPs in HSPA1A gene predict risk of coronary heart disease. PLoS One. 2009, 4(3):e4851. (*Co-first author) (SCI Impact Factor: 3.234)

Co-author Publications:

19. Deng Q, Dai X, Guo H, Huang S, Kuang D, Feng J, Wang T, Zhang W, Huang K, Hu D, Deng H, Zhang X, Wu T. Polycyclic Aromatic Hydrocarbons-Associated MicroRNAs and Their Interactions with the Environment: Influences on Oxidative DNA Damage and Lipid Peroxidation in Coke Oven Workers. Environ Sci Technol. 2014, 48(7):4120-8. (SCI Impact Factor: 5.331)

20. Yang B, Mo Z, Wu C, Yang H, Yang X, He Y, Gui L, Zhou L, Guo H, Zhang X, Yuan J, Dai X, Li J, Qiu G, Huang S, Deng Q, Feng Y, Guan L, Hu D, Zhang X, Wang T, Zhu J, Min X, Lang M, Li D, Hu FB, Lin D, Wu T, He M. A genome-wide association study identifies common variants influencing serum uric acid concentrations in a Chinese population. BMC Med Genomics. 2014, 7(1):10. (SCI Impact Factor: 3.914)

21. Zhou L, He M, Mo Z, Wu C, Yang H, Yu D, Yang X, Zhang X, Wang Y, Sun J, Gao Y, Tan A, He Y, Zhang H, Qin X, Zhu J, Li H, Lin X, Zhu J, Min X, Lang M, Li D, Zhai K, Chang J, Tan W, Yuan J, Chen W, Wang Y, Wei S, Miao X, Wang F, Fang W, Liang Y, Deng Q, Dai X, Lin D, Huang S, Guo H, Lilly Zheng S, Xu J, Lin D, Hu FB, Wu T. A genome wide association study identifies common variants associated with lipid levels in the Chinese population. PLoS One. 2013, 8(12):e82420. (SCI Impact Factor: 3.234)

22. Li J, Gui L, Wu C, He Y, Zhou L, Guo H, Yuan J, Yang B, Dai X, Deng Q, Huang S, Guan L, Hu D, Deng S, Wang T, Zhu J, Min X, Lang M, Li D, Yang H, Hu FB, Lin D, Wu T, He M. Genome-wide association study on serum alkaline phosphatase levels in a Chinese population. BMC Genomics. 2013, 14:684. (SCI Impact Factor: 4.041)

23. Qiu G, Feng Y, Li X, Deng H, Dai X, Deng Q, Huang S, He M, Guo H, Zhang X, Hu FB, Wu T. Disturbed heart rate variability: a dose-dependent response to elevated nitric oxide and carbon monoxide in exhaled breath. Int J Cardiol. 2013, 168(6):e155-7. (SCI Impact Factor: 6.175)

24. Dai X, Yuan J, Yao P, Yang B, Gui L, Zhang X, Guo H, Wang Y, Chen W, Wei S, Miao X, Li X, Min X, Yang H, Fang W, Liang Y, Hu FB, Wu T, He M. Association between serum uric acid and the metabolic syndrome among a middle- and old-age Chinese population. Eur J Epidemiol. 2013, 28(8):669-76. (SCI Impact Factor: 5.147)

25. Shi Y, Lian Y, Zhou L, Huang L, Zhang X, Guo H, Wu T, Cheng L, He M. Association between genetic variations in TFR2 gene and coronary heart disease in Chinese: a case-control study. J Cardiovasc Med (Hagerstown). 2013 Jun 7. [Epub ahead of print] (SCI Impact Factor: 1.407)

26. Dai X, Wu C, He Y, Gui L, Zhou L, Guo H, Yuan J, Yang B, Li J, Deng Q, Huang S, Guan L, Hu D, Zhu J, Min X, Lang M, Li D, Yang H, Hu FB, Lin D, Wu T, He M. A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population. Genet Epidemiol. 2013, 37(3):293-300. (SCI Impact Factor: 2.951)

27. Dong J, Jin G, Wu C, Guo H, Zhou B, Lv J, Lu D, Shi Y, Shu Y, Xu L, Chu M, Wang C, Zhang R, Dai J, Jiang Y, Yu D, Ma H, Zhao X, Yin Z, Yang L, Li Z, Deng Q, Cao S, Qin Z, Gong J, Sun C, Wang J, Wu W, Zhou G, Chen H, Guan P, Chen Y, Liu X, Liu L, Xu P, Han B, Bai C, Zhao Y, Zhang H, Yan Y, Liu J, Amos CI, Chen F, Tan W, Jin L, Wu T, Hu Z, Lin D, Shen H. Genome-wide association study identifies a novel susceptibility locus at 12q23.1 for lung squamous cell carcinoma in han chinese. PLoS Genet. 2013;9(1):e1003190. (SCI Impact Factor: 8.167)

28. Tang L, Wang H, Lu X, Jian X, Jin B, Zheng H, Li Y, Wang Q, Wu T, Guo H, Liu H, Guo T, Yu J, Yang R, Yang Y, Hu Y. Common genetic risk factors for venous thrombosis in the Chinese population. Am J Hum Genet. 2013, 92(2):177-87. (SCI Impact Factor: 10.987)

29. Wang F, Zhu J, Yao P, Li X, He M, Liu Y, Yuan J, Chen W, Zhou L, Min X, Fang W, Liang Y, Wang Y, Wei S, Liu J, Miao X, Lang M, Jiang X, Zhang P, Li D, Lu C, Wang X, Shi W, Zheng J, Guo H, Zhang X, Yang H, Hu FB, Wu T. Cohort profile: The Dongfeng-Tongji cohort study of retired workers. Int J Epidemiol. 2013, 42(3):731-740. (SCI Impact Factor: 9.197)

30. Chen M, He M, Min X, Pan A, Zhang X, Yao P, Li X, Liu Y, Yuan J, Chen W, Zhou L, Fang W, Liang Y, Wang Y, Miao X, Lang M, Zhang P, Li D, Guo H, Yang H, Hu FB, Wu T. Different physical activity subtypes and risk of metabolic syndrome in middle-aged and older Chinese people. PLoS One. 2013;8(1):e53258. (SCI Impact Factor: 3.534)

31. Lan Q, Hsiung CA, Matsuo K, Hong YC, Seow A, Wang Z, Hosgood HD 3rd, Chen K, Wang JC, Chatterjee N, Hu W, Wong MP, Zheng W, Caporaso N, Park JY, Chen CJ, Kim YH, Kim YT, Landi MT, Shen H, Lawrence C, Burdett L, Yeager M, Yuenger J, Jacobs KB, Chang IS, Mitsudomi T, Kim HN, Chang GC, Bassig BA, Tucker M, Wei F, Yin Z, Wu C, An SJ, Qian B, Lee VH, Lu D, Liu J, Jeon HS, Hsiao CF, Sung JS, Kim JH, Gao YT, Tsai YH, Jung YJ, Guo H, Hu Z, Hutchinson A, Wang WC, Klein R, Chung CC, Oh IJ, Chen KY, Berndt SI, He X, Wu W, Chang J, Zhang XC, Huang MS, Zheng H, Wang J, Zhao X, Li Y, Choi JE, Su WC, Park KH, Sung SW, Shu XO, Chen YM, Liu L, Kang CH, Hu L, Chen CH, Pao W, Kim YC, Yang TY, Xu J, Guan P, Tan W, Su J, Wang CL, Li H, Sihoe AD, Zhao Z, Chen Y, Choi YY, Hung JY, Kim JS, Yoon HI, Cai Q, Lin CC, Park IK, Xu P, Dong J, Kim C, He Q, Perng RP, Kohno T, Kweon SS, Chen CY, Vermeulen R, Wu J, Lim WY, Chen KC, Chow WH, Ji BT, Chan JK, Chu M, Li YJ, Yokota J, Li J, Chen H, Xiang YB, Yu CJ, Kunitoh H, Wu G, Jin L, Lo YL, Shiraishi K, Chen YH, Lin HC, Wu T, Wu YL, Yang PC, Zhou B, Shin MH, Fraumeni JF Jr, Lin D, Chanock SJ, Rothman N. Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia. Nat Genet. 2012 Dec;44(12):1330-5. (SCI Impact Factor:29.648)

32. Dong J, Hu Z, Wu C, Guo H, Zhou B, Lv J, Lu D, Chen K, Shi Y, Chu M, Wang C, Zhang R, Dai J, Jiang Y, Cao S, Qin Z, Yu D, Ma H, Jin G, Gong J, Sun C, Zhao X, Yin Z, Yang L, Li Z, Deng Q, Wang J, Wu W, Zheng H, Zhou G, Chen H, Guan P, Peng Z, Chen Y, Shu Y, Xu L, Liu X, Liu L, Xu P, Han B, Bai C, Zhao Y, Zhang H, Yan Y, Amos CI, Chen F, Tan W, Jin L, Wu T, Lin D, Shen H. Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population. Nat Genet. 2012, 15;44(8):895-9. (SCI Impact Factor:29.648)

33. Li X, Feng Y, Deng H, Zhang W, Kuang D, Deng Q, Dai X, Lin D, Huang S, Xin L, He Y, Huang K, He M, Guo H, Zhang X, Wu T. The dose-response decrease in heart rate variability: any association with the metabolites of polycyclic aromatic hydrocarbons in coke oven workers? PLoS One. 2012;7(9):e44562. (SCI Impact Factor: 3.534)

34. Huang G, Guo H, Wu T. Genetic variations of CYP2B6 gene were associated with plasma BPDE-Alb adducts and DNA damage levels in coke oven workers. Toxicol Lett. 2012, 211(3):232-8. (Second authors: SCI Impact Factor: 3.355)

35. Hu Z, Wu C, Shi Y, Guo H*, Zhao X, Yin Z, Yang L, Dai J, Hu L, Tan W, Li Z, Deng Q, Wang J, Wu W, Jin G, Jiang Y, Yu D, Zhou G, Chen H, Guan P, Chen Y, Shu Y, Xu L, Liu X, Liu L, Xu P, Han B, Bai C, Zhao Y, Zhang H, Yan Y, Ma H, Chen J, Chu M, Lu F, Zhang Z, Chen F, Wang X, Jin L, Lu J, Zhou B, Lu D, Wu T, Lin D, Shen H. A genome-wide association study identifies two new lung cancer susceptibility loci at 13q12.12 and 22q12.2 in Han Chinese. Nat Genet. 2011, 43(8):792-6. (co-second authors: SCI Impact Factor: 29.648)

36. Liu L, Yuan P, Wu C, Zhang X, Wang F, Guo H, Zhong R, Xu Y, Wu J, Yu D, Wu T, Zhang X, Nie S, Miao X, Lin D. Assessment of XPD Lys751Gln and XRCC1 T-77C polymorphisms in advanced non-small-cell lung cancer patients treated with platinum-based chemotherapy. Lung Cancer. 2011, 73(1):110-5. (SCI Impact Factor: 3.737)

37. Shi Y, Zhou L, Huang LH, Lian YT, Zhang XM, Guo H, Wu TC, Cheng LX, He MA. Plasma ferritin levels, genetic variations in HFE gene, and coronary heart disease in Chinese: a case-control study. Atherosclerosis. 2011, 218(2):386-90. (SCI Impact Factor: 3.971)

38. Liu L, Yuan P, Liu L, Wu C, Zhang X, Guo H, Zhong R, Xu Y, Wu J, Duan S, Rui R, Wu T, Nie S, Miao X, Lin D. A functional -77T>C polymorphism in XRCC1 is associated with risk of breast cancer. Breast Cancer Res Treat. 2011, 125(2):479-87. (SCI Impact Factor: 4.198)

39. Hsiung CA, Lan Q, Hong YC, Chen CJ, Hosgood HD, Chang IS, Chatterjee N, Brennan P, Wu C, Zheng W, Chang GC, Wu T, Park JY, Hsiao CF, Kim YH, Shen H, Seow A, Yeager M, Tsai YH, Kim YT, Chow WH, Guo H, Wang WC, Sung SW, Hu Z, Chen KY, Kim JH, Chen Y, Huang L, Lee KM, Lo YL, Gao YT, Kim JH, Liu L, Huang MS, Jung TH, Jin G, Caporaso N, Yu D, Kim CH, Su WC, Shu XO, Xu P, Kim IS, Chen YM, Ma H, Shen M, Cha SI, Tan W, Chang CH, Sung JS, Zhang M, Yang TY, Park KH, Yuenger J, Wang CL, Ryu JS, Xiang Y, Deng Q, Hutchinson A, Kim JS, Cai Q, Landi MT, Yu CJ, Park JY, Tucker M, Hung JY, Lin CC, Perng RP, Boffetta P, Chen CY, Chen KC, Yang SY, Hu CY, Chang CK, Fraumeni JF Jr, Chanock S, Yang PC, Rothman N, Lin D. The 5p15.33 locus is associated with risk of lung adenocarcinoma in never-smoking females in Asia. PLoS Genet. 2010, 6(8): e1001051. (SCI Impact Factor: 8.167)

40. Chen L, Guo H, Yuan J, He M, Chen D, Shi J, Yang J, Bai Y, Ju Y, Liu A, Yu Z, Li L, Sheng G, Fu J, Wu T, Chen X. Polymorphisms of GSTT1 and GSTM1 and increased micronucleus frequencies in peripheral blood lymphocytes in residents at an e-waste dismantling site in China. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2010, 45(4):490-7. (SCI Impact Factor: 1.135)

41. Wang F, He Y, Guo H, Li J, Yang Y, Wu Z, Zheng H, Wu T. Genetic variants of nucleotide excision repair genes are associated with DNA damage in coke oven workers. Cancer Epidemiol Biomarkers Prev. 2010, 19(1):211-8. (SCI Impact Factor: 4.324)

42. Wu C, Hu Z, Yu D, Huang L, Jin G, Liang J, Guo H, Tan W, Zhang M, Qian J, Lu D, Wu T, Lin D, Shen H. Genetic variants on chromosome 15q25 associated with lung cancer risk in Chinese populations. Cancer Res. 2009, 69(12):5065-72. (SCI Impact Factor: 9.284)

43. He M, Guo H, Yang X, Zhou L, Zhang X, Cheng L, Zeng H, Hu FB, Tanguay RM, Wu T. Genetic variations in HSPA8 gene associated with coronary heart disease risk in a Chinese population. PLoS One. 2010 Mar 16;5(3):e9684. (SCI Impact Factor: 3.534)

44. Yuan J, Chen L, Chen D, Guo H, Bi X, Ju Y, Jiang P, Shi J, Yu Z, Yang J, Li L, Jiang Q, Sheng G, Fu J, Wu T, Chen X. Elevated serum polybrominated diphenyl ethers and thyroid-stimulating hormone associated with lymphocytic micronuclei in Chinese workers from an E-waste dismantling site. Environ Sci Technol. 2008, 42(6):2195-200. (SCI Impact Factor: 5.481)

45. Wang J, Li X, Han X, Yang K, Liu B, Li Y, Wu P, Liu X, Yu K, Dai X, Yuan J, Yao P, Zhang X, Guo H, Wang Y, Chen W, Wei S, Miao X, Min X, Liang Y, Yang H, Hu FB, Wu T, He M. Serum creatinine levels and risk of metabolic syndrome in a middle-aged and older Chinese population. Clin Chim Acta. 2014 Dec 2;440C:177-182. (SCI Impact Factor: 2.764)

46. He M, Xu M, Zhang B, Liang J, Chen P, Lee JY, Johnson TA, Li H, Yang X, Dai J, Liang L, Gui L, Qi Q, Huang J, Li Y, Adair LS, Aung T, Cai Q, Cheng CY, Cho MC, Cho YS, Chu M, Cui B, Gao YT, Go MJ, Gu D, Gu W, Guo H, Hao Y, Hong J, Hu Z, Hu Y, Huang J, Hwang JY, Ikram MK, Jin G, Kang DH, Khor CC, Kim BJ, Kim HT, Kubo M, Lee J, Lee J, Lee NR, Li R, Li J, Liu J, Longe J, Lu W, Lu X, Miao X, Okada Y, Ong RT, Qiu G, Seielstad M, Sim X, Song H, Takeuchi F, Tanaka T, Taylor PR, Wang L, Wang W, Wang Y, Wu C, Wu Y, Xiang YB, Yamamoto K, Yang H, Liao M, Yokota M, Young T, Zhang X, Kato N, Wang QK, Zheng W, Hu FB, Lin D, Shen H, Teo YY, Mo Z, Wong TY, Lin X, Mohlke KL, Ning G, Tsunoda T, Han BG, Shu XO, Tai ES, Wu T, Qi L. Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci. Hum Mol Genet. 2014 Nov 26. pii: ddu583. [Epub ahead of print] (SCI Impact Factor: 6.677)

47. Dai X, Deng S, Wang T, Qiu G, Li J, Yang B, Feng W, He X, Deng Q, Ye J, Zhang W, He M, Zhang X, Guo H, Wu T. Associations between 25 lung cancer risk-related SNPs and polycyclic aromatic hydrocarbon-induced genetic damage in coke oven workers. Cancer Epidemiol Biomarkers Prev. 2014, 23(6):986-96. (SCI Impact Factor: 4.324)

48. Zhang R, Chu M, Zhao Y, Wu C, Guo H, Shi Y, Dai J, Wei Y, Jin G, Ma H, Dong J, Yi H, Bai J, Gong J, Sun C, Zhu M, Wu T, Hu Z, Lin D, Shen H, Chen F. A genome-wide gene-environment interaction analysis for tobacco smoke and lung cancer susceptibility. Carcinogenesis. 2014, 35(7):1528-35. (SCI Impact Factor: 5.266)

49. Chu M, Zhang R, Zhao Y, Wu C, Guo H, Zhou B, Lu J, Shi Y, Dai J, Jin G, Ma H, Dong J, Wei Y, Wang C, Gong J, Sun C, Zhu M, Qiu Y, Wu T, Hu Z, Lin D, Shen H, Chen F. A genome-wide gene-gene interaction analysis identifies an epistatic gene pair for lung cancer susceptibility in Han Chinese. Carcinogenesis. 2014, 35(3):572-7. (SCI Impact Factor: 5.266)

50. Zhu C, Bassig BA, Shi K, Boyle P, Guo H, Zheng T. Different time trends by gender for the incidence of Hodgkin's lymphoma among young adults in the USA: a birth cohort phenomenon. Cancer Causes Control. 2014, 25(8):923-31. (SCI Impact Factor: 2.961)

51. Machiela MJ, Hsiung CA, Shu X, Seow WJ, Wang Z, Matsuo K, Hong Y, Seow A, Wu C, Hosgood HD 3rd, Chen K, Wang J, Wen W, Cawthon R, Chatterjee N, Hu W, Caporaso NE, Park JY, Chen C, Kim YH, Kim YT, Landi MT, Shen H, Lawrence C, Burdett L, Yeager M, Chang I, Mitsudomi T, Kim HN, Chang G, Bassig BA, Tucker M, Wei F, Yin Z, An S, Qian B, Lee VH, Lu D, Liu J, Jeon H, Hsiao C, Sung JS, Kim JH, Gao Y, Tsai Y, Jung YJ, Guo H, Hu Z, Hutchinson A, Wang W, Klein RJ, Chung CC, Oh I, Chen K, Berndt SI, Wu W, Chang J, Zhang X, Huang M, Zheng H, Wang J, Zhao X, Li Y, Choi JE, Su W, Park KH, Sung SW, Chen Y, Liu L, Kang CH, Hu L, Chen C, Pao W, Kim Y, Yang T, Xu J, Guan P, Tan W, Su J, Wang C, Li H, Sihoe AD, Zhao Z, Chen Y, Choi YY, Hung J, Kim JS, Yoon H, Cai Q, Lin C, Park IK, Xu P, Dong J, Kim C, He Q, Perng R, Kohno T, Kweon S, Chen C, Vermeulen RC, Wu J, Lim W, Chen K, Chow W, Ji B, Chan JK, Chu M, Li Y, Yokota J, Li J, Chen H, Xiang Y, Yu C, Kunitoh H, Wu G, Jin L, Lo Y, Shiraishi K, Chen Y, Lin H, Wu T, Wong MP, Wu Y, Yang P, Zhou B, Shin M, Fraumeni JF Jr, Zheng W, Lin D, Chanock SJ, Rothman N, Lan Q. Genetic variants associated with longer telomere length are associated with increased lung cancer risk among never-smoking women in Asia: a report from the female lung cancer consortium in Asia. Int J Cancer. 2015 Jul 15;137(2):311-9. (SCI Impact Factor: 5.007)

 

Awards and Honors

1. National Youth Top Talent Support Program of National High-level Personnel of Special Support Program (The “Thousands-of-Talents Scheme”), 2015

2. 100 National Excellent Doctoral Dissertations in China, 2012.

3. New Century Excellent Talents in University of Ministry of Education of China, 2012

4. Excellent New Scholar Award of Huazhong University of Science and Technology, 2012.

5. Fazu Qiu Scholarship of Huazhong University of Science and Technology (2010)

6. Young investigator award in the 4th Cell Stress Society International (CSSI) Congress on Stress Responses in Biology and Medicine, Sapporo, Japan (2009)

7. Excellent Ph.D. Thesis Award of Huazhong University of Science and Technology (2009)

8. 3M Scholarship of Occupational Health (2008)

9. Public Welfare Award of Huazhong University of Science and Technology (2007)

10. Excellent Student Scholarship of Huazhong University of Science and Technology (2001-2005)

11. Excellent Student Scholarship of China (2004)

12. Educational Scholarship of the United Laboratories company of Hongkong (2002)

 

Project

1. Foundation for the Author of National Excellent Doctoral Dissertation of P.R. China (Grant no. 201484).

2. Program for New Century Excellent Talents in University of Ministry of Education of China, 2012 (grant no. NCET-12-0209)

3. Genetic and functional annotation of polymorphisms in key genes of the cell cycle process and their associations with lung cancer risk and prognosis. (The National Natural Science Foundation of China, grant no. 81272589)

4. Genetic variations in HSPB1, APEX1 and TP53 and DNA damage levels in coke oven workers (The National Natural Science Foundation of China, grant no. 81102102)

5. Association study of APEX1 polymorphisms and genetic damage levels in coke oven workers (Research Fund for the Doctoral Program of Higher Education of China, grant no. 20110142120026)

6. TagSNPs in HSPA1L-HSPA1A-HSPA1B cluster and lung cancer risk and survival (The Talent Introduction foundation of HUST)

7. Associations between genetic variations in pre-microRNA and DNA damage levels in coke oven workers (The Autonomous Innovation Foundation of HUST, grant no. 2011QN207)

 

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