Job title: Associate Professor

Phone: 86(27)15972176690

Email: junhe@mails.tjmu.edu.cn

Academic Areas: Histology and Embryology

Research Interests: The molecular mechanisms of calcium signaling through store-operated Ca2+ channels (SOCs),The Molecular mechanisms of insulin secretion and its regulation

Academic Degrees

PhD in Biomedical Engineering, 2005, Huazhong University of Science and Technology

MS in Physiology, 2001, West China Medical Center of Sichuan university

BS in clinical medicine, 1994, Southwest Medical University

Professional Experience

Associate Professor (2005-present), Department of Histology and Embryology, Tongji Medical College,Huazhong University of Science and Technology

Lecturer (1994-2001), Southwest Medical University 

Selected Publications

 

  • Pan JY, Yuan S, Yu T, Su CL, Liu XL, He J*, Li H. Regulation of L-type Ca2+ Channel activity and insulin secretion by Huntingtin-associated protein 1.J Biol Chem. 2016 Sep 13. pii: jbc.M116.727990. [Epub ahead of print]( Corresponding author)
  • Jun He, Tao Yu, Jing Ying Pan, He Li. Visualisation and identification of  the interaction between STIM1s in resting cells. PLoS ONE 2012; 7(3): e33377. doi:10.1371/journal.pone.0033377( Corresponding author)
  • Shun Liu, Jun He, Honglin Jin, Fei Yang, Jinling Lu, Jie Yang. Enhanced dynamic range in a genetically encoded Ca2+ sensor. BiochemBioph Res Co 2011; 412:155-159 (Co-first author)
  • Jun He, Hui Gong, QingmingLuo. BDNF acutely modulates synaptic transmission and calcium signalling in developing cortical neurons. Cell physiolbiochem2005; 16:69-76(First author)
  • Wang Z, Peng T, Wu H, He J, Li H. HAP1 helps to regulate actin-based transport of insulin-containing granules in pancreatic β cells. Histochem Cell Biol. 2015;144:39-48.
  • Shan-Shan Huang, Jun He, Dong-Ming Zhao, Xiao-Yuan Xu, Hui-Ping Tan, He Li. Effects of mutant Huntingtin on mGluR5-mediated dual signaling pathways: implications for therapeutic interventions.Cell MolNeurobiol  2010; 30:1107–1115
  • Austin Cape, Xingxing Chen, Chuan-En Wang, Ashley O’Neill, Yung-Feng Lin, Jun He, Xing-Shun Xu, Hong Yi, He Li, Shihua Li, Xiao-Jiang Li. Loss of Huntingtin-associated protein 1 impairs insulin secretion from pancreatic β−cells. Cell Mol Life Sci. 2012;69(8):1305-17

 

Courses Taught

  • Histology and Embryology (undergraduate)
  • Histochemical and Cytochemical Techniques (graduate)
  • Cell Biology (graduate)

 

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