Academic Degrees

PhD in Biochemistry and Molecular Biology, 2008, Wuhan University

BS in Biological Science, 2000, Hunan Normal University

Professional Experience

Professor (2015-present), Huazhong University of Science and Technology, Tongji Medical College, School of Basic Medicine,Department of Medical Genetics

Research Associate (2013-2015), Western University, Department of Biochemistry

Post-doctoral Fellow, (2008-2013), Western University, Department of Biochemistry

Selected Publications

1.Bian YY, Li L, Dong MM, Liu HD, Voss C, Cao X，Wang Y, Ye ML, Li SS,Zou HF. Ultra-deep tyrosine phospho-proteomics enabled by a phosphotyrosine superbinder.NAT CHEM BIOL 2016 12(11): 959-966

2. Cao X, Kaneko T, Li JS, Liu AD, Voss C, Li SS. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration. NAT COMMUN 2015 6:7721

3. Cao X, Voss C, Zhao B, Kaneko T, Li SS. Differential regulation of the activity of deleted in liver cancer 1 (DLC1) by tensins controls cell migration and transformation. P NATL ACAD SCI USA 2012 109(5)：1455-60.

4. Kaneko T^＊, Huang H^＊, Cao X, Voss C, Sidhu SS, Li SS. Superbinder SH2 domains act as antagonists of cell signaling. SCI SIGNAL 2012 5(243): ra68.

5. Cao X, Wang YF, Zhang CF, Gao WJ. Visual DNA microarrays for simultaneous detection of Ureaplasma urealyticum and Chlamydia trachomatis coupled with multiplex asymmetrical PCR. Biosens Bioelectron. 2006 22(3):393-8.

6. Cao X, Jiang Z, Wang Y, Gong R, Zhang C. Two multiplex real-time TaqMan

polymerase chain reaction systems for simultaneous detecting and serotyping of

Ureaplasma parvum. Diagn Microbiol Infect Dis. 2007（59）：109-111.

7. Cao X, Wang Y, Hu X, Qing H, Wang H. Real-time TaqMan polymerase chain

reaction assays for quantitative detection and differentiation of Ureaplasma

urealyticum and Ureaplasma parvum. Diagn Microbiol Infect Dis. 2007

57(4):373-8.

8. Zhao Y, Cao X, Zheng Y, Tang J, Cai W, Wang H, Gao Y, Wang Y. Relationship

between cervical disease and infection with human papillomavirus types 16 and 18,

herpes simplex virus 1 and 2. J Med Virol. 2012 84(12):1920-7.

9. Zhao Y, Cao X, Tang J, Zhou L, Gao Y, Wang J, Zheng Y, Yin S, Wang Y. A novel

multiplex real-time PCR assay for the detection and quantification of HPV16/18 and

HSV1/2 in cervical cancer screening. Mol Cell Probe. 2012 26(2):66-72.

10. Liu HH, Cao X, Yang Y, Liu MG, Wang YF. Array-based nano-amplification

technique was applied in detection of hepatitis E virus. J Biochem Mol Biol.

2006 39(3):247-52.

PATENTS

1. Diagnostic kit for Ureaplasma parvum DNA (PCR-Fluorescence Probing) (China, the 1st Inventor)

2. Diagnostic kit for Chlamydia Trachomatis DNA (PCR-Fluorescence Probing) (China, the 1st Inventor)

3. Diagnostic kit for Ureaplasma parvum and Chlamydia Trachomatis DNA (PCR-Fluorescence Probing) (China, the 2nd Inventor)

4. SH2 domain variants (PCT，the 3rd Inventor)

Awards and Honors

Registration Certificates for Medical Device of State FDA of China

1. Diagnostic kit for Ureaplasma parvum DNA (PCR-Fluorescence Probing) (No3401017)

2. Diagnostic kit for Chlamydia Trachomatis DNA (PCR-Fluorescence Probing) (No3401019)

3. Diagnostic kit for Ureaplasma parvum and Chlamydia Trachomatis DNA (PCR-Fluorescence Probing) (No3401015)

Courses Taught

1004221，Cell and Molecular Biology in Medicine (undergraduate)

1001101，The Cell Biology (undergraduate)

501.543, Progression of Medical Genetics (graduate)

510.816, Dysfunction of Receptors and Ion Channels in Neurological Disease (PhD)

Project

1. Exploring the molecular mechanisms of the regulation of PTEN and p110 on the GAP function of p85, Rac1 activity and fibroblast cell migration and transformation. National Natural Science Foundation of China, 2016-2019

2. Exploring the novel cellular signaling pathway of cell migration and metastasis. Natural Science Foundation of Hubei Province for Distinguished Young Scholars, 2016-2019

3. The investigation on the cancer and the novel technology of precision diagnostic based on the SH2-Superbinder. Natural Science Foundation of Wuhan for Distinguished Young Scholars, 2016-2018

4. Exploring the novel cellular signaling pathway of cell migration and its function on the metastasis. The Fundamental Research Funds for the Central Universities, 2015-2016