Selected Publications
1 Yang SS, Lin L, Liu Y, Wang J, Chu J, Zhang T, Ning LN, Shi Y, Fang YY, Zeng P, Wang JZ, Qiu MY*, Tian Q*. High Morphologic Plasticity of Microglia/Macrophages Following Experimental Intracerebral Hemorrhage in Rats. Int J Mol Sci. 2016 Jul 21;17(7). pii: E1181. doi: 10.3390/ijms17071181
2 Liu ZC, Chu J, Lin L, Song J, Ning LN, Luo HB, Yang SS, Shi Y, Wang Q, Qu N, Zhang Q, Wang JZ*, Tian Q*. SIL1 rescued Bip elevation related tau hyperphosphorylation in ER stress. Mol Neurobiol. 2016 Mar;53(2):983-94
3 Qu N, Zhou XY, Han L, Xu JX, Zhang T, Chu J, Chen Q, Wang JZ, Zhang Q*, Tian Q*. Combination of PPT with LiCl treatment prevented bilateral ovariectomy-induced hippocampal dependent cognition deficit in rats. Mol Neurobiol. 2016 Mar; 53(2):894-904.
4 Wang X, Pei L, Yan H, Wang Z, Wei N, Wang S, Yang X, Tian Q*, Lu Y*. Intervention of death-associated protein kinase 1-p53 interaction exerts the therapeutic effects against stroke. Stroke. 2014 Oct; 45(10):3089-91.
5 Jiang Q, Wang L, Guan Y, Xu H, Niu Y, Han L, Wei YP, Lin L, Chu J, Wang Q, Yang Y, Pei L, Wang JZ*, Tian Q*. Golgin-84-associated Golgi fragmentation triggers tau hyperphosphorylation by activation of cyclin-dependent kinase-5 and extracellular signal-regulated kinase. Neurobiol Aging. 2014 Jun; 35(6):1352-63.
6 Yao ZH, Kang X, Yang L, Niu Y, Lu Y, Gong CX, Tian Q*, Wang JZ*. Phenylbutyric acid protects against spatial memory deficits in a model of repeated electroconvulsive therapy. Curr Neurovasc Res. 2014 May; 11(2):156-67.
7 Lin L, Yang SS, Chu J, Wang L, Ning LN, Zhang T, Jiang Q, Tian Q*, Wang JZ*. Region-specific expression of tau, amyloid-β protein precursor, and synaptic proteins at physiological condition or under endoplasmic reticulum stress in rats. J Alzheimers Dis. 2014; 41(4):1149-63.
8 Wang L, Jiang Q, Chu J, Lin L, Li XG, Chai GS, Wang Q, Wang JZ*, Tian Q*. Expression of tau40 induces activation of cultured rat microglial cells. PLoS One. 2013 Oct 11;8(10):e76057
9 Lin L, Huang QX, Yang SS, Chu J, Wang JZ*, Tian Q*. Melatonin in Alzheimer’s Disease. Int. J. Mol. Sci. 2013, 14(7), 14575-14593
10 Zhao K, Wen R, Wang X, Pei L, Yang Y, Shang Y, Bazan N, Zhu LQ*, Tian Q*, Lu Y*. EPAC confers the seizure vulnerability via inhibition of SUR1 receptors. J Neurosci. 2013 May 15; 33(20):8861-5.
11 Qu N, Wang L, Liu ZC, Tian Q*, Zhang Q. Oestrogen receptor α agonist improved long-term ovariectomy-induced spatial cognition deficit in young rats. Int J Neuropsychopharmacol. 2013 Jun;16(5):1071-82
12 Liu XA, Song J, Jiang Q, Wang Q, Tian Q*, Wang JZ*. Expression of the hyperphosphorylated tau attenuates ER stress-induced apoptosis with upregulation of unfolded protein response. Apoptosis. 2012 Oct;17(10):1039-49
13 Liu ZC, Fu ZQ, Song J, Zhang JY, Wei YP, Chu J, Han L, Qu N, Wang JZ, Tian Q*. Bip Enhanced the Association of GSK-3β with Tau During ER Stress Both in vivo and in vitro. J Alzheimers Dis. 2012; 29(4):727-40
14 Wei W, Liu YH, Zhang CE, Wang Q, Wei Z, Mousseau DD, Wang JZ, Tian Q*, Liu GP*. Folate/vitamin-B12 prevents chronic hyperhomocysteinemia-induced tau hyperphosphorylation and memory deficits in aged rats. J Alzheimers Dis. 2011; 27:639-50
15 Yang XF, Yang Y, Fu ZQ, Li Y, Feng J, Luo JZ, Zhang QY, Wang Q, Tian Q*. Melatonin ameliorates Alzheimer-like pathological changes and spatial memory retention impairment induced by calyculin A. J Psychopharmacol. 2011; 25:1118-25
16 Fu ZQ, Yang Y, Song J, Jiang Q, Liu ZC, Wang Q, Wang JZ, Tian Q*. LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro. J Alzheimer Dis. 2010; 21:1107-17.
17 Liu XA, Liao K, Liu R, Wang HH, Zhang Y, Zhang Q, Wang Q, Tian Q*, Wang JZ*. Tau dephosphorylation potentiates apoptosis with the mechanisms involving a failed dephosphorylation/activation of Bcl-2. J Alzheimers Dis. 2010;19: 953-62.
18 Tian Q, Zhang JX, Zhang Y, Wu F, Tang Q, Wang C, Shi ZY, Zhang JH, Liu S, Wang Y, Zhang Q, Wang JZ. Biphasic effects of forskolin on tau phosphorylation and spatial memory in rats. J Alzheimer Disease 2009;17:631-42
19 Ling ZQ, Tian Q*, Wang L, Fu ZQ, Wang JZ*. Constant illumination induces Alzheimer-like damages with endoplasmic reticulum involvement and the protection of melatonin. J Alzheimer Disease 2009;16:287-300
20 Wang XC*, Du XX*, Tian Q*, Wang JZ. Correlation between choline signal intensity and acetylcholine level in different brain regions of rat. Neurochem Res. 2008;33(5):814-9. （*Equal contribution）
21 Zhang CE*, Tian Q*, Wei W, Pen JH, Liu GP, Zhou XW, Wang Q, Wang DW, Wang JZ. Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus. Neurobiol Aging 2008; 29(11): 1654-65（*Equal contribution）
22. Li X *, Lu F *, Tian Q *, Yang Y, Wang Q and Wang JZ. Activation of glycogen synthase kinase-3 induces Alzheimer-like tau hyperphosphorylation in rat hippocampus slices in culture. J Neural Transm. 2006;113(1):93-102（*Equal contribution）
23. Tian Q, Lin ZQ, Wang XC, Chen J, Wang Q, Gong CX, Wang JZ. Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit. Neuroscience. 2004; 126(2):277-284.
24. Tian Q, Wang JZ. Role of Serine/Threonine Protein Phosphatase in Alzheimer’s Disease. Neurosignals. 2002; 11(5): 262-269
1 Yang SS, Lin L, Liu Y, Wang J, Chu J, Zhang T, Ning LN, Shi Y, Fang YY, Zeng P, Wang JZ, Qiu MY*, Tian Q*. High Morphologic Plasticity of Microglia/Macrophages Following Experimental Intracerebral Hemorrhage in Rats. Int J Mol Sci. 2016 Jul 21;17(7). pii: E1181. doi: 10.3390/ijms17071181
2 Liu ZC, Chu J, Lin L, Song J, Ning LN, Luo HB, Yang SS, Shi Y, Wang Q, Qu N, Zhang Q, Wang JZ*, Tian Q*. SIL1 rescued Bip elevation related tau hyperphosphorylation in ER stress. Mol Neurobiol. 2016 Mar;53(2):983-94
3 Qu N, Zhou XY, Han L, Xu JX, Zhang T, Chu J, Chen Q, Wang JZ, Zhang Q*, Tian Q*. Combination of PPT with LiCl treatment prevented bilateral ovariectomy-induced hippocampal dependent cognition deficit in rats. Mol Neurobiol. 2016 Mar; 53(2):894-904.
4 Wang X, Pei L, Yan H, Wang Z, Wei N, Wang S, Yang X, Tian Q*, Lu Y*. Intervention of death-associated protein kinase 1-p53 interaction exerts the therapeutic effects against stroke. Stroke. 2014 Oct; 45(10):3089-91.
5 Jiang Q, Wang L, Guan Y, Xu H, Niu Y, Han L, Wei YP, Lin L, Chu J, Wang Q, Yang Y, Pei L, Wang JZ*, Tian Q*. Golgin-84-associated Golgi fragmentation triggers tau hyperphosphorylation by activation of cyclin-dependent kinase-5 and extracellular signal-regulated kinase. Neurobiol Aging. 2014 Jun; 35(6):1352-63.
6 Yao ZH, Kang X, Yang L, Niu Y, Lu Y, Gong CX, Tian Q*, Wang JZ*. Phenylbutyric acid protects against spatial memory deficits in a model of repeated electroconvulsive therapy. Curr Neurovasc Res. 2014 May; 11(2):156-67.
7 Lin L, Yang SS, Chu J, Wang L, Ning LN, Zhang T, Jiang Q, Tian Q*, Wang JZ*. Region-specific expression of tau, amyloid-β protein precursor, and synaptic proteins at physiological condition or under endoplasmic reticulum stress in rats. J Alzheimers Dis. 2014; 41(4):1149-63.
8 Wang L, Jiang Q, Chu J, Lin L, Li XG, Chai GS, Wang Q, Wang JZ*, Tian Q*. Expression of tau40 induces activation of cultured rat microglial cells. PLoS One. 2013 Oct 11;8(10):e76057
9 Lin L, Huang QX, Yang SS, Chu J, Wang JZ*, Tian Q*. Melatonin in Alzheimer’s Disease. Int. J. Mol. Sci. 2013, 14(7), 14575-14593
10 Zhao K, Wen R, Wang X, Pei L, Yang Y, Shang Y, Bazan N, Zhu LQ*, Tian Q*, Lu Y*. EPAC confers the seizure vulnerability via inhibition of SUR1 receptors. J Neurosci. 2013 May 15; 33(20):8861-5.
11 Qu N, Wang L, Liu ZC, Tian Q*, Zhang Q. Oestrogen receptor α agonist improved long-term ovariectomy-induced spatial cognition deficit in young rats. Int J Neuropsychopharmacol. 2013 Jun;16(5):1071-82
12 Liu XA, Song J, Jiang Q, Wang Q, Tian Q*, Wang JZ*. Expression of the hyperphosphorylated tau attenuates ER stress-induced apoptosis with upregulation of unfolded protein response. Apoptosis. 2012 Oct;17(10):1039-49
13 Liu ZC, Fu ZQ, Song J, Zhang JY, Wei YP, Chu J, Han L, Qu N, Wang JZ, Tian Q*. Bip Enhanced the Association of GSK-3β with Tau During ER Stress Both in vivo and in vitro. J Alzheimers Dis. 2012; 29(4):727-40
14 Wei W, Liu YH, Zhang CE, Wang Q, Wei Z, Mousseau DD, Wang JZ, Tian Q*, Liu GP*. Folate/vitamin-B12 prevents chronic hyperhomocysteinemia-induced tau hyperphosphorylation and memory deficits in aged rats. J Alzheimers Dis. 2011; 27:639-50
15 Yang XF, Yang Y, Fu ZQ, Li Y, Feng J, Luo JZ, Zhang QY, Wang Q, Tian Q*. Melatonin ameliorates Alzheimer-like pathological changes and spatial memory retention impairment induced by calyculin A. J Psychopharmacol. 2011; 25:1118-25
16 Fu ZQ, Yang Y, Song J, Jiang Q, Liu ZC, Wang Q, Wang JZ, Tian Q*. LiCl attenuates thapsigargin-induced tau hyperphosphorylation by inhibiting GSK-3β in vivo and in vitro. J Alzheimer Dis. 2010; 21:1107-17.
17 Liu XA, Liao K, Liu R, Wang HH, Zhang Y, Zhang Q, Wang Q, Tian Q*, Wang JZ*. Tau dephosphorylation potentiates apoptosis with the mechanisms involving a failed dephosphorylation/activation of Bcl-2. J Alzheimers Dis. 2010;19: 953-62.
18 Tian Q, Zhang JX, Zhang Y, Wu F, Tang Q, Wang C, Shi ZY, Zhang JH, Liu S, Wang Y, Zhang Q, Wang JZ. Biphasic effects of forskolin on tau phosphorylation and spatial memory in rats. J Alzheimer Disease 2009;17:631-42
19 Ling ZQ, Tian Q*, Wang L, Fu ZQ, Wang JZ*. Constant illumination induces Alzheimer-like damages with endoplasmic reticulum involvement and the protection of melatonin. J Alzheimer Disease 2009;16:287-300
20 Wang XC*, Du XX*, Tian Q*, Wang JZ. Correlation between choline signal intensity and acetylcholine level in different brain regions of rat. Neurochem Res. 2008;33(5):814-9. （*Equal contribution）
21 Zhang CE*, Tian Q*, Wei W, Pen JH, Liu GP, Zhou XW, Wang Q, Wang DW, Wang JZ. Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus. Neurobiol Aging 2008; 29(11): 1654-65（*Equal contribution）
22. Li X *, Lu F *, Tian Q *, Yang Y, Wang Q and Wang JZ. Activation of glycogen synthase kinase-3 induces Alzheimer-like tau hyperphosphorylation in rat hippocampus slices in culture. J Neural Transm. 2006;113(1):93-102（*Equal contribution）
23. Tian Q, Lin ZQ, Wang XC, Chen J, Wang Q, Gong CX, Wang JZ. Injection of okadaic acid into the meynert nucleus basalis of rat brain induces decreased acetylcholine level and spatial memory deficit. Neuroscience. 2004; 126(2):277-284.
24. Tian Q, Wang JZ. Role of Serine/Threonine Protein Phosphatase in Alzheimer’s Disease. Neurosignals. 2002; 11(5): 262-269
Chinese
