Academic Degrees

PhD in Medical Immunology, 2005, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

BS in Clinical Medicine, 1997, Tongji Medical University

Professional Experience

Lecturer(2005-2008), Associate Professor (2008-present), Tongji Medical College, Huazhong University of Science and Technology, Department of Immunology;

Visiting Scholar(2009-2010), Heidelberg University, Department of Immunology;

Teaching Assistant (1997-2000 ), Tongji Medical University, Experiment Center.

Selected Publications

1. Yang M, Zhang F, Qin K, Wu M, Li H, Zhu H, Ning Q, Lei P, Shen G. Glucose-Regulated Protein 78-Induced Myeloid Antigen-Presenting Cells Maintained Tolerogenic Signature upon LPS Stimulation. Front Immunol. 2016 Dec 01; 7:552. doi: 10.3389/fimmu.2016.00552.    

2.    Qing Jiang, Yuanli Sun, Zilong Guo, Mingpeng Fu, Qiang Wang, Huifen Zhu, Ping Lei, Guanxin Shen. Overexpression of GRP78 enhances survival of CHO cells in response to serum-deprivation and oxidative stress. Engineering in Life Sciences. Published on 01 Jan 2016, doi: 10.1002/elsc.201500152

3.    Zhang X, Zhang R, Yang H, Xiang Q, Jiang Q, He Q, Zhang T, Chen C, Zhu H, Wang Q, Ning Q, Li Y, Lei P, Shen G. Hepatitis B virus enhances cisplatin-induced hepatotoxicity via a mechanism involving suppression of glucose-regulated protein of 78 Kda. Chem Biol Interact. 2016, 254: 45-53.

4.    Tang Y, Jiang Q, Ou Y, Zhang F, Qing K, Sun Y, Lu W, Zhu H, Gong F, Lei P, Shen G. BIP induces mice CD19(hi) regulatory B cells producing IL-10 and highly expressing PD-L1, FasL. Mol Immunol. 2016,69:44-51.

5.    He Q, Sun X, Chu C, Jiang Q, Zhu H, He Y, Yue T, Wang R, Lei P*, Shen G. Endocytosis of a functionally enhanced GFP-tagged transferrin receptor in CHO cells. PLoS One. 2015,10(3):e0122452. doi: 10.1371/journal.pone.0122452.

6.    Hongbo Liu, Yan Gan, Yanheng Wu, Hui Weng, Ping Lei*, Guanxin Shen. Effects of different lysis buffers of nucleic acid purification kit on the stability of influenza virus RNA. Future Virology. 2014,9(6), 549-555.

7.    Yang J, Zhu H, Tan Z, He F, Sun X, Hong Y, Hu H, Bian J, Lin Y, Lei P*, Shen G. Comparison of two functional kappa light-chain transcripts amplified from a hybridoma. Biotechnol Appl Biochem. 2013,60(3):289-297

8.    Wang Q, Shu R, He H, Wang L, Ma Y, Zhu H, Wang Z, Wang S, Shen G, Lei P*. Co-silencing of Birc5 (survivin) and Hspa5 (Grp78) induces apoptosis in hepatoma cells more efficiently than single gene interference. Int J Oncol. 2012,41: 652-660.

Courses Taught

1001112 Immune biology (undergraduate)

1001111 Medical Immunology (undergraduate)

1001113 Medical Immunology (undergraduate)

1003631 Medical Immunology (undergraduate)

1003632 Medical Immunology (undergraduate)

1409271 Tropical Medicine (undergraduate)

510.512 Basic Immunology(graduate)

510.534 Molecular Immunology(graduate)

510.523 Experimental Immunology (graduate)

510.814 Proceedings of Immunology (graduate)

510.808 Medical Research(graduate)

Project

1. Therapeutic potential of tranferrin receptor redirected T cells in cancer. Natural Science Foundation of China, 2016-2019.

2. Development of multifunctional antibodies against transferrin receptor. Hi-tech research and development program of China. 2012-2015.

3. Research on regulatory DC induction by GRP78. Natural Science Foundation of China, 2012-2014.