Academic Degrees

PhD in Department of Pharmacology, 2009, Huazhong University of Science and Technology, Wuhan

MS Department of Pharmacology, 2004, Huazhong University of Science and Technology, Wuhan

BS in Clinic Medicine, 1999, Tongji Medical College

Professional Experience

Associate Professor (2012-present), Huazhong University of Science and Technology, Department of Pharmacology

Lecturer (2004-2012), Huazhong University of Science and Technology, Department of Pharmacology

Visiting Scholar (2007-2009), Department of Pharmacology, Mainz University, German

Assistant (1999-2004), Huazhong University of Science and Technology, Department of Pharmacology

Selected Publications

1. 
   

2. Li C^#, Lu Q^#, Huang P, Fu T, Li C, Guo L, Xu X*.Activity-dependent downregulation of M-Type (Kv7) K⁺ channels surface expression requires the activation of iGluRs/Ca²⁺/PKC signaling pathway in hippocampal neuron. Neuropharmacology. 2015 Aug;95:154-67.

3. 
   

4. Li Y^#, Xu XL^#, Zhao D, Pan LN, Huang CW, Guo LJ, Lu Q*, Wang J.TLR3 ligand Poly IC Attenuates Reactive Astrogliosis and Improves Recovery of Rats after Focal Cerebral Ischemia. CNS Neurosci Ther. 2015 Nov;21(11):905-13.

(3) Li CJ, Lu Y, Zhou M, Zong XG, Li C, Xu XL, Guo LJ*, Lu Q*. Activation of GABAB Receptors Ameliorates Cognitive Impairment via Restoring the Balance of  HCN1/HCN2 Surface Expression in the Hippocampal CA1 Area in Rats With Chronic Cerebral Hypoperfusion. Mol Neurobiol. 2014 Oct;50(2):704-20.

(4) Pan LN, Zhu W, Li Y, Xu XL, Guo LJ, Lu Q*, Wang J. Astrocytic Toll-like receptor 3 is associated with ischemic preconditioning-induced protection against brain ischemia in rodents. PLoS One. 2014 Jun 10;9(6):e99526.

(5) Pan LN, Zhu W, Li C, Xu XL, Guo LJ, Lu Q*. Toll-like receptor 3 agonist Poly I:C protects against simulated cerebral ischemia in vitro and in vivo. Acta Pharmacol Sin. 2012 Oct;33(10):1246-53.

1. 
   

2. Lu Q, Xia N, Xu H, Guo L, Wenzel P, Daiber A, Münzel T, Förstermann U, Li H. Betulinic acid protects against cerebral ischemia-reperfusion injury in mice by reducing oxidative and nitrosative stress.Nitric Oxide. 2011 Apr 30;24(3):132-8.

Courses Taught

1001051  Pharmacology (undergraduate)

1412061  Cosmeceutical for skin protection  (undergraduate)

1411342  Proper liftstyle against modern disease&subhealth  (undergraduate)

1411892  Rational drug use (undergraduate)

510.520  Methodology of advanced pharmacology  (graduate)

Project

1. SOCS1/3 negative regulation of TLR4/MyD88 signaling pathway involved in brain inflammation inhibiting during cerebral ischemia. National Natural Science Foundation of China (Regional Fund), 2017-2020, Cooperation. 2. The effects and mechanisms of Toll-like Receptor-mediated TRIF Signaling Pathway in Cerebral Ischemic Preconditioning. National Natural Science Foundation of China, 2011-2013. 3. SOCS3 signaling pathway in cerebral ischemic preconditioning. The Fundamental Research funds for the central universities, HUST, 2013.01-2014.12. 4. Glia glutamate transporter in cerebral ischemic preconditioning and the mechanism of PKC signal regulation. Ministry of Education, 40th batch fund for returned scholars, 2011-2012. 5. Protective Mechanisms of tea polyphenols in Vascular Dementia. Natural Science Foundation of Hubei Province, 2007-2009.