Academic Degrees

PhD in Neurobiology, 2009, Huazhong University of Science and Technology

MS in Medical genetics, 2002, Huazhong University of Science and Technology

BS in Clinical Medicine, 1999, Taishan Medical College

Professional Experience

Associate Professor (2012-present), Huazhong University of Science and Technology, Department of  Neurobiology;

Research Associate (2006-2012), Huazhong University of Science and Technology, Department of  Neurobiology;

Selected Publications

1. 
   

2. Meng X#, Chu G#, Yang Z, Qiu P, Hu Y, Chen X, Peng W, Ye C, He FF, Zhang C. Metformin Protects Neurons against Oxygen-Glucose Deprivation/Reoxygenation -Induced Injury by Down-Regulating MAD2B. Cell Physiol Biochem. 2016,40(3-4):477-485.

3. 
   

4. Wang X, Yang Z, Sun Y, Zhou H, Chu G, Zhang J, Meng X . Ethanol activation of PKA mediates single-minded 2 expression in neuronal cells. Mol Neurobiol. 2015,52(3):1234-1244.

5. 
   

6. Wang X#, Chu G#, Yang Z, Sun Y, Zhou H, Li M, Shi J, Tian B, Zhang C, Meng X*. Ethanol directly induced HMGB1 release through NOX2/NLRP1 inflammasome in neuronal cells. Toxicology. 2015,334:104-110.

7. 
   

8. Meng X#, Wang X, Tian X, Yang Z, Li M, Zhang C*, Protection of neurons from high glucose-induced injury by deletion of MAD2B. J Cell Mol Med, 2014, 18(5):844-51.

9. 
   

10. Meng XF#, Wang XL, Tian XJ, Yang ZH, Chu GP, Zhang J, Li M, Shi J, Zhang C*. Nod-Like Receptor Protein 1 Inflammasome Mediates Neuron Injury under High Glucose. Mol Neurobiol, 49(2):673-84.

11. 
    

12. Wang X#, Song Y, Chen L, Zhuang G, Zhang J, Li M, Meng XF*. Contribution of single-minded 2 to hyperglycaemia-induced neurotoxicity. Neurotoxicology. 35:106-12, 2013.

13. 
    

14. Meng X#, Tian X, Wang X, Gao P, Zhang C*. A novel binding protein of single-minded 2: the mitotic arrest-deficient protein MAD2B. Neurogenetics, 13(3):251-60, 2012.

15. 
    

16. Zhang C#, Tian X, Luo Y, Meng X*. Ginkgolide B attenuates ethanol-induced neurotoxicity through regulating NADPH oxidases. Toxicology, 287(1-3):124-30, 2011.

Courses Taught

510.508 Basis of Neurobiology (undergraduate)

510.521 Basic techniques and methods in Neurobiology (undergraduate)

1004333 Central nervous system and sensory organs (graduate)

Project

1. Role of Sim2 and MAD2B in clathrin-mediated endocytosis . Natural Science Foundation of Hubei Province, 2011-2013

2. Role of Down syndrome critical gene Sim2 binding to MAD2B in synaptic plasticity. Natural Science Foundation of China 2012-2015

3. Histone acetylation modification in mental retardation of Down syndrome. Fundamental Research Funds for the Central Universities. 2013-2015

4. mir-99a/AC in mental retardation of Down syndrome. Natural Science Foundation of China 2015-2018.

5. MAD2B-mediated neuronal cell re-entry in the cognitive dysfunction of diabetes mellitus. Natural Science Foundation of China 2017-2020.