YU Bing

Author: Source: Date:October 4, 2017 Cilk Times:[]

                           

Job title:  Associate Professor

Phone: 86(27)18627756183                                

Email: yubing@hust.edu.cn                                

Academic Areas: Medical Microbiology

Research Interests: The molecular mechanisms of mammaliancellsrecognizevirus-derivednucleicacidsusingadefined setof intracellularsensorsand the molecular mechanisms of HBV development of hepatocellular carcinoma (HCC).

Academic Degrees

PhD in department of immunology of Tongji Medical College of Huazhong University of Science and Technology, 2005

MS in department of immunology of Tongji Medical College of Huazhong University of Science and Technology, 2002

BS in clinical medicine, 1993, Hubei University of Medicine

Professional Experience



  • Associate Professor (2005-present), Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Scienceand Technology, Wuhan 430030, China


  • Post-doctor (2009-2012), UMR5236 CNRS,UM1,UM2, CPBS, Montpellier, France


  • Physician (1993-2001), Hubei Zhongshan Hospital


Selected Publications



  1. Wei Wei, Wang Sufei, Ni Ming, Yu Bing*Advances in intracellular DNA sensors of PYHIN family and mechanisms of viral evasion of innate immune responses. Journal of microbes and infectious. Aug. 25, 2016, 11(4): 252-256.


  2. Wang J, Yu B, Tian D, Ni M. Rhamnolipid but not motility is associated with the initiation of biofilm seeding dispersal of Pseudomonas aeruginosa strain PA17. J Biosci. 2013 Mar; 38(1):149-56.


  3. Chamontin C#, Yu B#, Racine PJ, Darlix JL, Mougel M. MoMuLV and HIV-1 nucleocapsid proteins have a common role in genomic RNA packaging but different in late reverse transcription. PLoS One. 2012;7(12):e51534.


  4. Ni M, Yu B*, Huang Y, Tang Z, Lei P, Shen X, Xin W, Zhu H, Shen G. Homology modelling and bivalent single-chain Fv construction of anti-HepG2 single-chain immunoglobulin Fv fragments from a phage display library. Journal of Bioscience. 2008, Dec, 33(5):691-697.


  5. ZhangXiaoyong, Ni Ming, ChenShanshan, Li Tingting, Yu Bing*, Lu Mengji. EndogenousLiverMicroRNA RegulatesHBV GeneExpressionandReplication. Journal of Medical Molecule Biology. 2008; 5(3): 189-193


  6. Shanshan Chen, Ming Ni, Yu Bing*, TingtingLv, Mengji Lu, Feili Gong. Construction and Identification of a human liver specific microRNA eukaryotic expression vector. Cellular & Molecular Immunology. 2007, Dec,4(6): 473-477.


  7. Yu B, Ni M, Li WH, Lei P, Xing W, Xiao DW, Huang Y, Tang ZJ, Zhu HF, Shen GX. Human scFv antibody fragments specific for HCC selected from a large human naive scFv phage display library. World J Gastroenterol. 2005 Jul 14;11(26):3985-9.


  8. Lei P, Li WH, Liao WJ, Yu Bing, Zhu HF, Shao JF, Shen GX.  Construction and co-expression of bicistronic plasmid encoding human WEE1 and stem cell factor. ActaBiochimBiophys Sin. 2005; 37(2): 107-12


  9. Yu Bing, Ni Ming, Lei Ping, LiWenhan, ZhuHuifen, Zhang Yue, TangZhenjie, Chen Xin, ShenGuanxin.Identification and sequence analysis of scFvs binding specifically to HepG2.


    1. Chinese Journal of immunology. 2005; 21(5): 179-182



  10. Wang Qian, Zhu Huifen, Cao Liming, Yu Bing, Zhou Huarong, and Shen Guanxin.   Construction and Biological effects in vitro of Double-directed Tissue-Specific HSV-TK/GCV Anti-tumor System. The Chinese-German Journal of Clinic Oncology 2003; 2(3): 184-187


Courses Taught



  • Medical Microbiology (undergraduate)


  • Infectious and tumors (graduate)


  • Transgene technology by adenovirus(graduate)


Project



  1. The study of identification new siRNA fragments for anti-Hantavirus. Natural Science Foundation of Hubei Province, 2007-2009(Grant NO.2006ABA143)


  2. Gene therapy by targeting lung cancer cells. Object of scientific research of Hubei Province, 2007-2009 (Grant NO.2006AA301C22)


  3. Anti-HBV replication by double scFvs targeting. Ph.D. Program Foundation of Ministry of Education of China, 2008-2010(Grant NO.20070487111)


  4. Study on the AIDS monitoring in Wuhan. Science Foundation of Disease Prevention and Control Center of Wuhan, China, 2008-2009


  5. Study on the regulatory mechanism of virus replication by MLV nucleocapsid. Science Foundation of Engineeringand Medicine Crossing, Huazhong University of Science and Technology. 2011-2012


  6. Study on the mechanism of IFI16 sensorssuppressing HBV replication. Science Foundation of autonomouslyinnovation, Huazhong University of Science and Technology. 2016-2018


  7. Study on the mechanism of HBV down regulating IFI16 expression. Science Foundation of National Health and Family Planning Commission of Hubei Province. 2016-2018


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