XI Jiaoya

Author: Source: Date:October 4, 2017 Cilk Times:[]

                           

Job title: Associate Professor of Physiology

Phone: 13638667518                                

Email: zhengyall@hotmail.com                                

Academic Areas: Stem Cells Research, Cardiovascular Physiology

Research Interests: cardiac differentiation, calcium handling, cardiac tissue engineering

Academic Degrees

PhD in Physiology, 2009, University of Cologne, Germany

MS in Physiology, 2005, Tongji Medical College, Huzhong University of Science and Technology

BS, 2000, Tongji Medical College, Huzhong University of Science and Technology

Professional Experience

Associate Professor (2012-present), Huazhong University of Science and Technology, Department of Physiology;

Lecturer (2005-2012), Huazhong University of Science and Technology, Department of Physiology;

Junior Lecturer (2000-2005), Huazhong University of Science and Technology, Department of Physiology.

Selected Publications



  1. Luo X, Zhong B, Hong X, Cui Y, Gao Y, Yin M, Tang M, Hescheler J, Xi J*. Puerarin Exerts a Delayed Inhibitory Effect on the Proliferation of Cardiomyocytes Derived from Murine ES Cells via Slowing Progression through G2/M Phase. Cell Physiol Biochem. 2016;38(4):1333-42.


  2. Yin M, Yuan Y, Cui Y, Hong X, Luo H, Hu X, Tang M, Hescheler J, Xi J*. Puerarin Suppresses the Self-Renewal of Murine Embryonic Stem Cells by Inhibition of REST-MiR-21 Regulatory Pathway. Cell Physiol Biochem. 2015;37(2):527-36.


  3. Wang L, Cui Y, Tang M, Hu X, Luo H, Hescheler J, Xi J*. Puerarin facilitates T-tubule development of murine embryonic stem cell-derived cardiomyocytes. Cell Physiol Biochem. 2014;34(2):383-92.


  4. Jiang YD, Li WS, Yu C, Wang L, Sun XX, Xi JY*. [Acquirement and evaluation of murine ventricular extracellular matrix]. Sheng Li Xue Bao. 2014 Dec 25;66(6):709-17. Chinese.


  5. Yin MM, Cui YR, Wang L, Wang JY, Gao Y, Xi JY*. [Progress on PI3K/Akt signaling pathway regulating self-renewal and pluripotency of embryonic stem cells]. Sheng Li Xue Bao. 2014 Apr 25;66(2):223-30. Chinese.


  6. Cheng Y, Wang L, Tang M, Yin M, Cui Y, Liang H, Song Y, Hu X, Luo H, Gao Y, Wang J, Hescheler J, Xi J*. Effects of puerarin on cardiac differentiation and ventricular specialization of murine embryonic stem cells.  Cell Physiol Biochem. 32(4):789-800, 2013.


  7. Tang M, Yin M, Tang M, Liang H, Yu C, Hu X, Luo H, Baudis B, Haustein M, Khalil M, Sarić T, Hescheler J, Xi J*. Baicalin maintains late-stage functional cardiomyocytes in embryoid bodies derived from murine embryonic stem cells. Cell Physiol Biochem. 32(1):86-99, 2013.


  8. Xi J, Khalil M, Spitkovsky D, Hannes T, Pfannkuche K, Bloch W, Saric T, Brockmeier K, Hescheler J*, Pillekamp F*. Fibroblasts support functional integration of purified embryonic stem cell-derived cardiomyocytes into avital myocardial tissue. Stem Cells Dev. 20(5):821-30, 2011 May.


  9. Xi J, Khalil M, Shishechian N, Hannes T, Pfannkuche K, Liang H, Fatima A, Haustein M, Suhr F, Bloch W, Reppel M, Sarić T, Wernig M, Jänisch R, Brockmeier K, Hescheler J*, Pillekamp F*. Comparison of contractile behavior of native murine ventricular tissue and cardiomyocytes derived from embryonic or induced pluripotent stem cells. FASEB J. 24(8):2739-2751, 2010 Aug.


  10. Pfannkuche K#, Liang H#, Hannes T#, Xi J#, Fatima A, Nguemo F, Matzkies M, Wernig M, Jaenisch R, Pillekamp F, Halbach M, Schunkert H, Sarić T, Hescheler J*, Reppel M*. Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. Cell Physiol Biochem. 24(1-2):73-86, 2009.


Courses Taught

1001131 Physiology (undergraduate)
1001043 Functional Experiment I (undergraduate)
1001064 Functional Experiment II (undergraduate)
1409101 Advances in Cardiovascular Physiology (undergraduate)

510.502 Advances in Physiology (graduate)

510.817 Stem Cell Techniques and Applications (graduate)

Project

1.     Effect of puerarin on functional development of sarcoplasmic reticulum for calcium handling of cardiomyocytes derived from murine embryonic stem cells. NSFC project (Nr.: 31100828), 2012.01-2014.12.

2. Investigation of contractile maturation of stem cell-derived cardiomyocytes in a novel in vitro transplantation model. Scientific Research Foundation for Returned Scholars, Ministry of Education of China, 2011.08-2014.12.

3.    Effect of puerarin on functional development of sarcoplasmic reticulum for calcium handling of cardiomyocytes derived from murine embryonic stem cells. Natural Science Foundation of Hubei Province (Nr.: 2011CDB363), 2012.01-2013.12.

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