WANG Hui

Author: Source: Date:October 4, 2017 Cilk Times:[]

                           

Job title: Lecturer

Phone: 86(27)18995591866                                

Email: wanghuipitt@hust.edu.cn                                

Academic Areas: Medical Genetics

Research Interests: Sterile inflammation and innate immune, sepsis and microRNA, ADAR1 and liver inflammation

Academic Degrees

PhD in Medical Immunology, 2007, Huazhong University of Science and technology,

MS in Medical genetics, 2004, Huazhong University of Science and technology

BS in Clinical medicine, 1999, Tongji medical college

Professional Experience

Lecturer (2004-present), Huazhong University of Science and Technology, Department of Medical genetics;

Visiting Scholar(2011-2012), University of Pittsburgh Medical centre, Department of surgery

Teaching assistant (1999-2004), Huazhong University of Science and Technology, Department of Medical genetics;  

Selected Publications

1. Hui Wang#, Guoliang Wang, Liyong Zhang, Junbin Zhang, Jinxiang Zhang, Qingde Wang* & Timothy R. Billiar*. ADAR1 Suppresses the Activation of Cytosolic RNA-Sensing Signaling Pathways to Protect the Liver from Ischemia/Reperfusion Injury. Scientific Reports, 2016, 6:20248|DOI: 10.1038/srep20248.

2. Hui Wang#, Haojun Shi, Jing Zhang, Guoliang Wang, Jinxiang Zhang, Fagang Jiang, and Qing Xiao*. Toll-Like Receptor 4 in Bone Marrow-Derived Cells Contributes to the Progression of Diabetic Retinopathy. Mediators of Inflammation, 2014, 2014, Article ID 858763.

3. Wang Hui#, Zhang Jinxiang*, Wu Heshui, Li Zhuoya, Zheng Qichang. Bone marrow and non-bone marrow TLR4 regulates hepatic ischemia/reperfusion injury. Biochemical and Biophysical Research Communications, 2009, 389(2):328-332.

4. Zhang JinXiang#*, Wang Hui#, Xiao Qing, Liang HuiFang, Li ZhuoYa, Jiang ChunFang, Wu HeShui, Zheng QiChang. Hyaluronic Acid Fragments Evoke Kupffer Cells via TLR4 Signaling Pathway. Science in China Series C: Life Sciences, 2009, 52(2):147-154.

5. Wang Hui#, Li Zhuoya, Wu Heshui, Wang Yang, Jiang Chunfang, Zheng Qichang and Zhang Jinxiang*. Endogenous danger signals trigger hepatic ischemia/reperfusion injury through toll-like receptor 4/nuclear factor-kappa B pathway. Chinese Medical Journal, 2007, 120(6):509-514.

6. Wang Hui#,Zhang Jinxiang,Feng Wei,Zhang Shu,Liang Huifang,Wang Yang,Zheng Qichang,Li Zhuoya*. PIN1 gene overexpression and β-catenin gene mutation/expression in hepatocellular carcinoma and their significance. Journal of Huazhong University of Science and Technology (Med Sci), 2007, 27(1):54-57.

7. Wang Hui#, Zhang Jinxiang*, Wu Heshui, Jiang Chunfang, Zheng Qichang, Li Zhuoya. Inhibition of RAW264.7 macrophage inflammatory cytokines release by small haparin RNAi targeting TLR4. Journal of Huazhong University of Science and Technology (Med Sci), 2006, 26(5):500-503.

Courses Taught

1001122 Medical Genetics (undergraduate)
1001121 Medical Genetics (graduate)
510.543 Advances in Medical Genetics (graduate)
510.805 Advanced Medical Genetics (Ph.D)

Project

1. ADAR1 limits RIG-I RNA-sensing pathways and suppresses IFN production to protect against liver ischemia and reperfusion injury, Natural Science Foundation of China, 2016-2019.

2. TLR4 enhance the protection effect of BMSC against liver ischemia and reperfusion injury. Program Foundation of National Health and Family planning Commission of Hubei Province, 2013-2014.

3. Adjustment of TLR4 on BMSC treatment effect against acute respiratory distress syndrome. Natural Science Foundation of Hubei Province, 2013-2014.

4. Low molecular weight of Hyaluronic act as potential ligand to activate TLR4 to induce liver ischemia and reperfusion injury. Natural Science Foundation of China, 2008-2010.

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