Job title: Lecturer
Phone: 86(27)15327273879
Email: guanfei@hust.edu.cn
Academic Areas: Human Parasitology
Research Interests: host immunity of parasitic diseases
Academic Degrees
PhD in Pathogenic Biology, 2009, Tongji Medical College, Huazhong University of Science and Technology
BS in Clinical Medicine, 2004, Tongji Medical College, Huazhong University of Science and Technology
Professional Experience
Lecturer (2009-present), Huazhong University of Science and Technology, Department of Pathogenic Biology
Selected Publications
Q.R. Chen, F. Guan, S.M. Song, J.K. Jin, D.S. Lei, C.M. Chen, J.H. Lei, Z.W. Chen, A.O.Niu. Allograft inflammatory factor-1 alleviates liver disease of BALB/c mice infected with Schistosomajaponicum. Parasitol Res. 2014, 113(7):2629~2639.
Q. Yu, H. Yang,F. Guan, Y.M.Feng, X.L. Yang,Y.H. Zhu. Detection of IgG insera of patients with schistosomiasis japonica by developing magnetic affinityenzyme-linked immunoassay based on recombinant 14-3-3 protein. Trans R Soc Trop Med Hyg. 2014, 108(1), 37-41.
F. Guan, X.Hou, G.Nie, Y. Xiao, Q. Zhang, W.Q. Liu, Y.L. Li, J.H. Lei. Effect of Trichinellaspiralis infection on the immune response to HBV vaccine in a mouse model. Foodborne Pathog Dis. 2013, 10(10), 882-887.
Y.Wang, Y.M.Huang, F.Guan,Y.Xiao, J.Deng, H.Y.Chen, X.L.Chen, J.R.Li, H.J.Huang,C.W.Shi.Hypoxia-Inducible Factor-1alpha and MAPK Co-Regulate Activation of Hepatic Stellate Cells upon Hypoxia Stimulation. PLos One.2013, 8(9), e74051.
Q.R.Chen, F.Guan,D. J. Yan, D. S.Lei, L. Fu, H. S. Xia, Y. H. Zhu, Z. W. Chen, A. O. Niu. The dynamic expression of allograft inflammatory factor-1 in hepatic tissues and splenic cells of BALB/c mice with Schistosomajaponicuminfection. Tissue Antigens. 2012, 79(1), 33-41.
6. J.H. Lei, F. Guan, H.Xu, L. Chen, B.T. Su, Y. Zhou, T. Wang, Y.L. Li, W.Q. Liu.Application of an immunomagnetic bead ELISA based on IgY for detection of circulating antigen in urine of mice infected with Schistosomajaponicum. Veterinary Parasitology. 2012, 187(1-2), 196-202.
7. F.Guan,A.O.Niu, S. W.Attwood, Y.L.Li, B.Zhang,Y.H. Zhu. Molecular phylogenetics of Triculine snails (Gastropoda :Pomatiopsidae) from southern China. Molecular phylogenetics and evolution. 2008, 48(2), 702-707.
Courses Taught
1001021 Pathogenic Biology (Human Parasitology) (undergraduate)
1409271Tropical Medicine (undergraduate)
1409131 Immunology of parasitic disease (undergraduate)
Project
1. Loop-mediated isothermal amplification for diagnosis of Schistosomajaponicum infection. Program Foundation of health and family planning commission of Hubei Province, 2017-2019.
2. Immunological regulation of AIF-1 in polarization of Th2 response in mice infected with Schistosomajaponicum. Natural Science Foundation of China, 2013-2015
3. DNA barcoding and phylogenetics of Oncomelaniahupensis. Program Foundation of Health Department of Hubei Province, 2010-2012
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