Position: Associate Professor in School of Pharmacy, Tongji Medical College
Email: huangjr@hust.edu.cn
Academic areas: Pharmaceutical Chemistry
General Introduction:
Research in our group focuses on the new methodology development as well as pharmaceutical synthesis. Undergraduate students, graduate students, postdoctoral fellows and visiting scholars are always welcome to join us.
Academic Degrees
2009-09 to 2014-06 (Ph.D) Sichuan University, China West China School of Pharmacy
2005-09 to 2009-06 (B.S.) Sichuan University, China West China School of Pharmacy
Professional Experiences
2018-02 to Present (Associate Professor. & Doctoral Supervisor.)
Huazhong University of Science and Technology, China
Tongji School of Pharmacy
2015-09 to 2017-10 (Postdoc.)
RWTH Aachen University, Germany
Organische Chemie Department
2014-08 to 2015-07 (Postdoc.)
Okinawa Institute of Science and Technology Graduate University, Japan
Chemistry and Chemical Bioengineering Unit
Publications
1.Ji-Rong Huang, Carsten Bolm* Microwave-Assisted Synthesis of Heterocycles by Rhodium(III)-Catalyzed Annulation of N-Methoxyamides with α-Chloroaldehydes, Angew. Chem. Int. Ed. 2017, 56, 15921-15925 (SCI, IF 11.709)
2.Ji-Rong Huangǂ, Muhammad Sohaiǂ, Tohru Taniguchi, Kenji Monde, Fujie Tanaka*, Formal (4+1) Cycloaddition and Enantioselective Michael–Henry Cascade Reactions To Synthesize Spiro[4,5]decanes and Spirooxindole Polycycles, Angew. Chem. Int. Ed. 2017, 56, 5853-5857. (SCI, IF 11.709)
3.Ji-Rong Huangǂ, Liu Qinǂ, Yu-Qin Zhu, Qiang Song, Lin Dong*, Multi-site cyclization via initial C-H activation using a rhodium(III) catalyst: rapid assembly of frameworks containing indoles and indolines, Chem. Commun. 2015, 51, 2844-2847. (SCI, IF 6.567)
4.Ji-Rong Huangǂ, Qiang Songǂ, Yu-Qin Zhu, Liu Qin, Zhi-Yong Qian*, Lin Dong*, Rhodium(III)-Catalyzed Three-Component Reaction of Imines, Alkynes, and Aldehydes through C−H Activation, Chem. Eur. J. 2014, 20, 16882-16886. (SCI, IF 5.771)
5.Lin Dong*, Ji-Rong Huang, Chuan-Hua Qu, Qian-Ru Zhang, Wei Zhang, Bo Han, Cheng Peng*, Rhodium(III)-catalyzed Vinylic sp2 C-H Bond Functionalization: Efficient Synthesis of Pyrido[1,2-α]benzimidazoles and Imidazo[1,2-α]pyridines, Org. Biomol. Chem. 2013, 11, 6142-6149. (SCI, IF 3.559)
6.Ji-Rong Huang, Chuan-Hua Qu, Qian-Ru Zhang, Xun-Hao Sun, Lin Dong*, Ying-Chun Chen*, “Rhodium(III)-Catalyzed Direct Selective C(5)-H Oxidative Annulations of 2-Substituted Imidazoles and Alkynes by Double C-H Activation, Org. Lett. 2013, 15, 1878-1881. (SCI, IF 6.732)
7.Ji-Rong Huang, Lin Dong*, Bo Han, Cheng Peng*, Ying-Chun Chen*, Synthesis of Aza-Fused Polycyclic Quinolines via Double C-H Bond Activations, Chem. Eur. J. 2012, 18, 8896-8900. (SCI, IF 5.771)
8.Ji-Rong Huang, Hai-Lei Cui, Jie Lei, Xun-Hao Sun, Ying-Chun Chen*, Organocatalytic chemoselective asymmetric N-allylic alkylation of enamides, Chem. Commun. 2011, 47, 4784-4786. (SCI, IF 6.567)
9.Lin Dong,* Chuan-Hua Quǂ, Ji-Rong Huangǂ, Wei Zhang, Qian-Ru Zhang, Jin-Gen Deng, Rhodium-catalyzed Spirocyclic Sultams Synthesis by [3+2] Annulation with Cyclic N-Sulfonyl Ketimines and Alkynes, Chem. Eur. J. 2013, 19, 16537-16540. (SCI, IF 5.771)
10.Qian-Ru Zhang, Ji-Rong Huang, Wei Zhang, Lin Dong*, Highly Functionalized Pyridines Synthesis from N-Sulfonyl Ketimines and Alkynes Using the N−S Bond as an Internal Oxidant, Org. Lett. 2014, 16, 1684-1687. (SCI, IF 6.732)
11.Hai-Lei Cui, Ji-Rong Huang, Jie Lei, Zhao-Feng Wang, Shi Chen, Li Wu, Ying-Chun Chen*, Direct Asymmetric Allylic Alkylation of Butenolides with Morita Baylis Hillman Carbonates, Org. Lett. 2010, 12, 720-723. (SCI, IF 6.732)
12.Lin Wu, Qian-Ru Zhang, Ji-Rong Huang, Yang Li, Fu Su*, Lin Dong*, The application of Morita-Baylis-Hillman reaction: Synthetic studies on perophoramidine. Tetrahedron, 2017, 73, 3966-3972. (SCI, IF 2.651)
ǂ Co-first author
Awards and Honors
l Alexander von Humboldt-Stiftung, 2015-2017.
l Top Academic Stars of Sichuan University, 2013.
l Outstanding graduate Award, Sichuan University, 2013.
l National Scholarship for Outstanding PhD Students, Ministry of Education, 2013.
l Excellent Doctoral Candidates Award, Sichuan University, 2012, 2013.
l The Special Winner of the Fosun Pharmaceutical Top Grade Scholarship, 2012.
l The Medical Scholarship by Daiichi-Sankyo Corporation, 2011.
l Excellent Postgraduates Award, Sichuan University, 2011.
l The TEDA Asymchem Scholarship, 2007.
Courses Taught
l Pharmaceutical Synthesis
l The Principle of Drug Design