LIU Xiqiu

Author: Source: Date:September 4, 2019 Cilk Times:[]


  Position: Associate Professor in School of Pharmacy, Tongji Medical College


Academic areas: Pharmaceutics

General Introduction

My research interests focus on biomimetic materials, drug screening models and cancer therapy.

Academic Degrees

lPh.D. in Biomaterials, 2012, University of Science and Technology of China, China

lB.S. in Biology, 2007, University of Science and Technology of China, China

Professional Experiences

lAssociate Professor (December 2016 - Current): Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

lResearch Fellow (April 2013 - December 2016):National Center for Scientific Research in France (CNRS), Grenoble, France

lPost-Doctoral Researcher (October 2012 - March 2013): Grenoble Institute of Technology, Grenoble, France

lGraduate Research Assistant (September 2007 - August 2012): School of Life Sciences, University of Science and Technology of China, Hefei, China

Selected Publications

1.Tang R.Z., Gu S.S., Chen X.T., He L.J., Wang K.P. andLIU X.Q.*A Immobilized Transforming Growth Factor-Beta 1 in a Stiffness-Tunable Artificial Extracellular Matrix Enhances Mechanotransduction in the Epithelial Mesenchymal Transition of Hepatocellular Carcinoma.ACS Applied Materials & Interfaces, In press

2.LIU X.Q.*and Tang R.Z.; Localized delivery of chemokine for in vitro manipulation of hepatocellular carcinoma cell behaviors during the epithelial–mesenchymal transition.Journal of Biomaterials Applications, 2018, 32, 945–956.

3.LIU X.Q.*and Tang R.Z.; Biological responses to nanomaterials: understanding nano-bio effects on cell behaviors.Drug Delivery, 2017, 24, 1-15.

4.Wang K.P., Cheng F., Pan X.L., Zhou T.,LIU X.Q., Zheng Z.M., Luo L., and Zhang Y.*; Investigation of the transport and absorption of angelica sinensis polysaccharide through gastrointestinal tract both in vitro and in vivo.Drug Delivery, 2017, 24, 1360-1371.

5.LIU X.Q.*, Fourel L., Dalonneau F., Sadir R., Lortat-Jacob H., Weidenhaupt M., Albiges-Rizo C., and Picart C.*; Biomaterial-enabled delivery of SDF-1α at the ventral side of breast cancer cells reveals a crosstalk between cell receptors to promote the invasive phenotype.Biomaterials,2017, 127, 61-74.

6.Chang H.,LIU X.Q.,Hu M., Zhang H., Li B.C., Ren K.F., Albiges-Rizo C., Picart C.* and Ji J. *; Substrate Stiffness Combined with Hepatocyte Growth Factor Modulates Endothelial Cell Behavior.Biomacromolecules,2016, 17, 2767−2776.

7.LIU X.Q.*, Picart C.*; Layer-by-layer assemblies for cancer research and treatments,Advanced Materials, 2016, 28, 1295–1301.

8.Dalonneau F.,LIU X.Q.(co-first author),Sadir R., Almodovar J., Mertani HC., Albiges-Rizo C., Bruckert F., Weidenhaupt M., Lortat-Jacob H., and Picart C.*; The effect of delivering the chemokine SDF-1α in a matrix-bound manner on myogenesis.Biomaterials,2014, 35, 4525–4535.

9.LIU X.Q., Sun C.Y., Yang X.Z., and Wang J.*; Polymeric-micelle-based nanomedicine for siRNA delivery.Particle & Particle Systems Characterization,2013,30, 211-228.

10.LIUX.Q., Xiong M.H., Shu X.T., Tang RZ., and Wang J.*; Therapeutic delivery of siRNA silencing HIF-1 Alpha with micellar nanoparticles inhibits hypoxic tumor growth.Molecular Pharmaceutics,2012, 9, 2863-2874.

11.LIU X.Q., Song W.J., Sun T.M., Zhang P.Z., Wang J.*; Targeted delivery of antisense inhibitor of miRNA for antiangiogenesis therapy using cRGD-functionalized nanoparticles.Molecular Pharmaceutics,2011, 8, 250-259.

12.Yang W., Pan C.Y.,*LIU X.Q., and Wang J.; Multiple functional hyperbranched poly(amido amine) nanoparticles: synthesis and application in cell imaging.Biomacromolecules,2011, 12, 1523-1531.

13.LIU X.Q., Du, J.Z., Zhang C.P., Zhao F., Yang X.Z., and Wang J.*; Brush-shaped polycation with poly(ethylenimine)-b-poly(ethylene glycol) side chains as highly efficient gene delivery vector.International Journal of Pharmaceutics,2010, 392, 118-126.

14.Wu J.,LIU X.Q., Wang Y.C., and Wang J.*; Template-free synthesis of biodegradable nanogels with tunable sizes as potential carriers for drug delivery.Journal of Materials Chemistry,2009, 19, 7856-7863.

15.Yuan Y.Y.,LIU X.Q.,Wang Y.C., and Wang J.*; Gold nanoparticles stabilized by thermosensitive diblock copolymers of poly(ethylene glycol) and polyphosphoester.Langmuir,2009, 25, 10298-10304.

16.Wang Y.C.,LIU X.Q.(co-first author),Sun T.M., Xiong M.H., and Wang J.*; Functionalized micelles from block copolymer of polyphosphoester and poly(e-caprolactone) for receptor-mediated drug delivery.Journal of Controlled Release,2008, 128, 32-40.

Awards and Honors

lBest Research Article Award in 2017 China Biomedical Engineering Conference, 3rdPrize, 2017

lRecognition Award of MedEngin Business Plan Competition, 2017

lNomination Award of Prix de l’Entrepreneuriat Club France, 2016

lAmbassador of the European Association for Cancer Research, 2016

lBest Poster Award in International Forum of Biomedical Materials, Hangzhou, China, October 28th-30th, 2014

lDiscussion Leader Honor in Gordon-Merck Research Seminar: Drug Carriers in Medicine & Biology, Waterville Valley, USA,August 16th-17th, 2014

lChinese Academy of Sciences President Award for the PhD defense, 2012

lPoster Award in 9thWorld Biomaterials Congress, 2012

lOutstanding Graduate award of University of Science and Technology of China, 2012

lGeneral Electric (GE) Foundation Tech Award, 1stPrize, 2011

lChinese Academy of Sciences “Zhu Li Yue Hua” Award for Graduate Students, 2011

lGlaxoSmithKline (GSK) scholarship for graduate students in China, 2010

lPresentation Award of Academic Forum of PhD students in China, 1stPrize, 2009

lGE Foundation Tech Award, 2ndPrize, 2009

l“DongGang” scholarship for graduate students in China, 2008

Courses Taught

lCalculus (in English)

lPhysical Chemistry (both in Chinese and in English)


1.National Natural Science Foundation of China (No. 81803108), Dynamic models with tunable stiffness and growth factor for study of cell behaviors and molecular mechanisms of hepatocellular carcinoma, 2019-2021,210,000

2.The Fundamental Research Fund for the Central Universities (No. 2018KFYYXJJ023), In vitro fabrication of a tunable extracellular matrix model to study cellular behaviors and drug responses of hepatocellular carcinoma, 2018-2020,80,000

3.Natural Science Foundation of Hubei Province (No. 2018CFB113), In vitro study of the mechanical environment on cell behaviors and drug responses, 2018-2019,50,000

4.The Talent Starting Grant from Huazhong University of Science and Technology in China (No. 3004514110) , In vitro cell microenvironment construction and study of biological functions at interfaces, 2016-2019,500,000

5.Young Investigator grant the Association Recherche contre le Cancer (ARC) of France (No. PDF20121206052), Délivrance de chimiokines par la surface d'un biomatériau par un film à base de biopolymères: impact sur l'adhesion et la migration de myoblastes et cellules cancéreuses, 2013-2016,90,000

Address:  Hangkong Road 13, Wuhan, China
Tel: +86 87542457(Admission Office)  Tel: +86 83692919(International Cooperation) Office)
Tongji Medical College Huazhong University of Science and Technology