Position: Associate Professor in School of Pharmacy, Tongji Medical College of HUST

Phone: 86-13807194659

Email: zqtcm@163.com

Academic Areas: Natural Medicine Chemistry, Pharmacology

Research Interests: extraction, separation, purification, structure identification and pharmacological activities of compounds from fungi and natural herbs

Academic Degrees

Postdoc in Pharmaceutics, 2012, University of Minnesota, America;

B.S. in Pharmacy, 1992, and M.S in Pharmacy, 2001, Hubei Univ of Traditional Chinese Medicine, Wuhan, China.

PhD in Pharmacology, 2009, Huazhong Univ Sci Tech, Wuhan, China.

Professional Experience

Associate Professor (2009-present); Tongji School of Pharmacy , HUST, China

Lecture (2001-2009); Tongji School of Pharmacy , HUST, China

Pharmacist (1992-1998);Hubei Provincial Hospital of Traditional Chinese Medicine, China.

Selected Publications

1. Zhang Q, Yu Y, Li J, Qun Zhou*, et al. Anti-arthritic activities of ethanol extracts of Circaea mollis Sieb. & Zucc. (whole plant) in rodents. Journal of Ethnopharmacology, 2018, 225: 359–366

2. Changxing Qi^(#), Mengting Liu^(#), Qun Zhou^(#), Weixi Gao, Chunmei Chen, Yongji Lai, Zhengxi Hu, Yongbo Xue, Jinwen Zhang, Dongyan Li, Xiao-Nian Li, Qing Zhang, Jianping Wang,^* Hucheng Zhu*, and Yonghui Zhang. BACE1 Inhibitory Meroterpenoids from the Fungus Aspergillus terreus. J. Nat. Prod. 2018, 81, 1937−1945

3. Changxing Qi^(#), Weixi Gao^(#), Danyingzi Guan^(#), Jianping Wang, Mengting Liu, Chunmei Chen, Hucheng Zhu, Yuan Zhou, Yongji Lai*, Zhengxi Hu*; Qun Zhou*, Yonghui Zhang*. Butenolides from a Marine-Derived Fungus Aspergillus terreus with Antitumor Activities Against Pancreatic Ductal Adenocarcinoma Cells. Bioorganic & Medicinal Chemistry,  26(22), 5903-5910

4. Changxing Qi^(#), Weixi Gao^(#), Jianping Wang^(#), Mengting Liu, Jinwen Zhang, Chunmei Chen, Zhengxi Hu, Yongbo Xue, Dongyan Li, Qing Zhang, Yongji Lai*, Qun Zhou*, Hucheng Zhu*, Yonghui Zhang*. Terrusnolides A-D, new butenolides with anti-inflammatory activities from an endophytic Aspergillus from Tripterygium wilfordii. Fitoterapia, 2018, 130: 134–139

5. Mengting Liu^(#), Qun Zhou^(#), Jianping Wang^(#), Junjun Liu, Changxing Qi, Yongji Lai, Hucheng Zhu, Yongbo Xue, Zhengxi Hu * and Yonghui Zhang*. Anti-inflammatory butenolide derivatives from the coral-derived fungus Aspergillus terreus and structure revisions of aspernolides D and G, butyrolactone VI and 4', 8〞-diacetoxy butyrolactone VI. RSC Adv., 2018, 8, 13040-13047

6. Chang-xing Qi^(#), Qun Zhou^(#), Yuan Zhou, Zeng-wei Luo, Chong Dai, Hu-cheng Zhu, Chun-mei Chen, Yong-bo Xue, Jian-ping Wang, Ya-fen Wang, Ya-ping Liu, Ming Xiang, Wei-guang Sun, Jin-wen Zhang*, Yong-hui Zhang*. Kinsenoside: A Promising Bioactive Compound from Anoectochilus Species. Current Medical Science, 2018, 38(1): 1-8

7. Qun Zhou, Limin Shi, Sayantan Chattoraj, Changquan Calvin Sun. Preparation and characterization of surface-engineered coarse microcrystalline cellulose through dry coating with silica nanoparticles. Journal of Pharmaceutical Sciences. 2012, 101(11):4258-4266.

8. Qun Zhou*, Jingjing Wang, Beidi Meng, Junqi Cheng, Guoping Lin*, Dan Zhen, Jiachun Chen. Distribution and sources of organochlorine pesticides in agricultural soils from central China. Ecotoxicology and Environmental Safety, 2013, 93: 163-170.

9. Jianqun Yuan, Limin Shi, Wei-Jhe Sun, Jiachun Chen, Qun Zhou*, Changquan Calvin Sun*. Enabling direct compression of formulated danshen powder by surface engineering. Powder technology, 2013, 241: 211-218.

10. Qun Zhou, Limin Shi, William Marinaro, Qun Lu, Changquan Calvin Sun*. Improving manufacturability of an ibuprofen powder blend by surface coating with silica nanoparticles. Powder technology. 2013, 249：290–296.

11. Qun Zhou, Jianqiu Zhou, Jiachun Chen, Xiaogang Wang. Karyotype analysis of medicinal plant Liriope spicata var. prolifera (Liliaceae). Biologia. 2009, 64 (4): 680-683.

12. Xingchu Gong, Shao-Yu Chang, Frederick Osei-Yeboah, Shubhajit Paul, Sathyanarayana Reddy Perumalla, Limin Shi, Wei-Jhe Sun, Qun Zhou, Changquan Calvin Sun*. Dependence of tablet brittleness on tensile strength and porosity. International Journal of Pharmaceutics. 2015, 493:208-213.

13. Zhiping Wang, Junbiao Wu, Qun Zhou, Hua Fan, Yifei Wang, Tongsheng Chen. In Vitro and in Vivo Antitumor Efficacy of Curcumol Nanosuspension Against H22 Tumor. Advanced Materials Research Vols, 2014, 998-999:151-155.

14. Zhiping Wang, Qun Zhou, Hua Fan, Yifei Wang. Preparation of lyophilized powder of oral Pueraria flavonoids nanosuspension and determination of dissolution rates of its four effective components. Chinese Traditional and Herbal Drugs, 2014, 45 (5): 635-641.

15. Luan Yuan Tian, Jia Chun Chen*, Jin Bo Fang, Qun Zhou, Xue Bai, Jian Qiu Zhou, Xiang Hong Chen. A New Monosaccharide from Swertia punicea Hemsl. Chinese Chemical Letters. 2009, 20:684-686.

16. Xianghong Chen, Xue Bai, Yihui Liu, Luanyuan Tian, Jianqiu Zhou, Qun Zhou, Jinbo Fang, Jiachun Chen*.Anti-diabetic effects of water extract and crude polysaccharides from tuberous root of Liriope spicata var. prolifera in mice. Journal of Ethnopharmacology. 2009, 122(2):205-209.

17. Xue Bai, Xianghong Chen, Yihui Liu, Luanyuan Tian, Qun Zhou, Shenghong Liu, Jinbo Fang, Jiachun Chen*. Effects of water extract and crude polysaccharides from Liriope spicata var. prolifera onInsR/IRS-1/PI3K pathway and glucose metabolism in mice. Journal of Ethnopharmacology. 2009, 125: 482-486

18. ZhipingWang,JunbiaoWu,Qun Zhou,YifeiWang,Tongsheng Chen, Berberine Nanosuspension Enhances Hypoglycemic Efficacy on Streptozotocin Induced Diabetic C57BL/6 Mice, Evidence-Based Complementary and Alternative Medicine, Vol 2015, 2015

19. Yanhong Yu, Wenliang Lu, Jiajia Li, Changquan Calvin Sun, Qun Zhou. Research about improving flowability of powder of Chinese herbs extracts by surface modification technology. China Journal of Chinese Material Medical, 2014, 39(23):4590-4595.

20. Zhiping Wang, Qun Zhou, Hua Fan, Yifei Wang. Preparation of lyophilized powder of oral Pueraria flavonoids nanosuspension and determination of dissolution rates of its four effective components. Chinese Traditional and Herbal Drugs, 2014，45（5）：635-641.

21. Qianxia Fu, Qun Zhou, Zhiping Wang, Hua Fan. Preparation of Pueraria flavonoids nanosuspension and the research of its hypoglycemic effects. Lishizhen Medicine and Materia Medica Research, 2014, 25（11）：2664-2666.

22. Xiangping Meng,Qun Zhou, Zhiping Wang, Yifei Wang. Preparation of lyophilized powder in oral Pueraria flavonoids loaded solid lipid nanoparticles and determination of release rate of its four effective components. Chinese Traditional and Herbal Drugs, 2014，45（17）：2467-2474.

Courses Taught

Pharmacognosy

Project

1．Research about traditional Chinese medicine extract powder modified by nanocoating technology (Fund projects of natural science of Hubei Province, 2015CFB495, 2015.1-2016.12)

2．Research about new coating modification technology of Chinese herbal medicine extract powder(Independent innovation fund of Huazhong University of Science and Technology, 2015QN157, 2015.1-2016.12)

3．Research about Circaea mollis alcohol extract on rat adjuvant arthritis effect and mechanism(Innovation and entrepreneurship training program of Huazhong University of Science and Technology, 11,2015.1-2015.12)

4．Remediation technology of soil contaminated with heavy metals( Scientific research project on environmental protection of Hubei Province, 2016.1-2016.12)

5．Co-crystal preparation and solubility improvement of Salvianolic acid B (Innovation and entrepreneurship training program of Huazhong University of Science and Technology, 2016.1-2016.12)

6．Research about the relationship between tobacco leaf tissue morphology and quality traits(National Tobacco Monopoly Bureau Key subsidy project "high quality and disease resistant white rib tobacco new variety selective breeding", 110200601004, subproject, 2006.9-2010.12)

7．Gas chromatographic method for determination of organochlorine pesticide residues in tobacco planting soil(China Tobacco standardization research project, YC/T-19 number [2009]100, 2009.1-2010.12)

8．Surface engineered microcrystalline cellulose for direct compression (University of Minnesota research program, 2011.5-2012.5)

9．Surface Engineering of an Ibuprofen Formulation for Superior Manufacturability (The United States pharmaceutical company Merck, 2011.8-2012.6)

10．Research about anti diabetic effect and resource quality of six kinds of Swertia plants produced in Hubei (NSFC, 30970282, 2010.01-2012.12)

11．Preclinical study on new drugs of Radix Ophiopogonis Polysaccharide(Major new drug discovery, 2011ZX09102-004-02, Major project, 2011.1-2013.12)

12．Research about Chinese herbal compound drug candidate of "diabetes in drinking water" prescription for the treatment of type II diabetes. (Major projects of technological innovation in Hubei Province)

13． Preclinical Study of compound Smilax scobinicaulis capsule(Hubei Furen Pharmacy project, 2008.11-2014.12)

14．Research about hypoglycemic effect and structure of uniform polysaccharide in Hubei geoherbs Ophiopogon japonicus(NSFC, 30873373, 2009.1-2011.12)