Associate Professor
Phone: 027-83692745
Email: pmchenzl@hust.edu.cn
Academic Areas:medicinal chemistry, chemical biology
Research Interests:novel and efficient methodology to construct chiral heterocycle, novel small molecules drug design and development
Academic Degrees
PhD in Organic Chemistry, 2013, Hong Kong University of Science and Technology, Hong Kong, China;
MS in Organic Chemistry, 2009, Shanghai Institute of Organic Chemistry, Chinese Academy of Science, Shanghai, China.
B.S in Applied Chemistry, 2006, Tongji University, Shanghai
Professional Experience
Associate Professor (2016.11-present); Tongji Pharmacy School, HUST
Postdoc Research Associate (2014.11-2016.11) The Elsheman School of Pharmacy, University of North Carolina at Chapel Hill
Postdoc Research Associate (2013.9-2014.10) Department of Chemistry, Duke University
Research Associate (2009.7-2011.1) Shanghai Unitris Biopharm. Co. Ltd
Selected Publications
Bioactive Alkaloid‐Type Polycycles through Efficient Catalytic Asymmetric Multicomponent Aza‐Diels‐Alder Reaction of Indoles with Oxetane as Directing Group,Chen, Z.; Wang, B.; Wang, Z.; Zhu, G.; Sun, J. Angew. Chem., Int. Ed. 2013, 52, 2027‐2031
Enantio- and Diastereoselective Assembly of Tetrahydrofuran and Tetrahydropyran Skeletons with All‐Carbon Quaternary Stereocenters, Chen, Z; Sun, J. Angew. Chem., Int.Ed. 2013, 52, 13593‐13596.
Catalytic Enantioselective Assembly of Tetrahydroisoquinolines and Their Analogues Bearing A C‐4 Stereocenter: A Formal Synthesis of (+)‐(8S,13R)‐Cyclocelabenzine. Chen, Z1.; Wang, Z1.; Sun, J. (1: equal contribution) Chem. Eur. J. 2013, 19, 8426‐8430.
Synthesis of o‐Aminophenols via a Formal Insertion Reaction of Arynes into Hydroxyindolinones, Chen, Z.; Wang, Q. Org. Lett., 2015, 17, 6130.
A Versatile and Highly Stereoselective Synthesis of Diethyl (1‐Aminoalkyl)thiophosphonates ,Chen Z, Li J, Yuan C, Synthesis, 2009, 3939‐3940
Project
Asymmetric Michael addition by photo-catalyst polyoxometalates and small organocatalyst (NSFC 21602011 2017.1-2019.12).
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