XIONG Bo

Author: Source: Date:October 10, 2017 Cilk Times:[]

                           

Job title: Professor

Phone: 027-83691052                                

Email: bxiong@hust.edu.cn                                

Academic Areas: Human Genetics/ Neurodevelopmental diseases/ Forensic Biology

Research Interests: Identification and characterization of genes that are associated with neurodevelopmental disorders

Academic Degrees

Ph.D., Baylor College of medicine, USA, 2013

Master, Tsinghua University, China, 2007

BA, Tsinghua University, China, 2003

Professional Experience

2016-present, professor, department of forensic medicine, HUST, Wuhan, China

2013-2015, Postdoc fellow, department of genome sciences, University of Washington, Seattle, USA

Selected Publications

1Holly AF Stessman#, Bo Xiong#, Bradley P Coe1, Tianyun Wang, Kendra Hoekzema, Michaela Fenckova, Malin Kvarnung, Jennifer Gerdts, Sandy Trinh, Nele Cosemans, Laura Vives, Janice Lin, Tychele N Turner, Gijs Santen, Claudia Ruivenkamp, Marjolein Kriek, Arie van Haeringen, Emmelien Aten, Kathryn Friend, Jan Liebelt, Christopher Barnett, Eric Haan, Marie Shaw, Jozef Gecz, Britt-Marie Anderlid, Ann Nordgren, Anna Lindstrand, Charles Schwartz, R Frank Kooy, Geert Vandeweyer, Celine Helsmoortel, Corrado Romano, Antonino Alberti, Mirella Vinci, Emanuela Avola, Stefania Giusto, Eric Courchesne, Tiziano Pramparo, Karen Pierce, Srinivasa Nalabolu, David G Amaral, Ingrid E Scheffer, Martin B Delatycki, Paul J Lockhart, Fereydoun Hormozdiari, Benjamin Harich, Anna Castells-Nobau, Kun Xia, Hilde Peeters, Magnus Nordenskjöld, Annette Schenck, Raphael A Bernier, Evan E Eichler. Targeted sequencing identifies 91 neurodevelopmental-disorder risk genes with autism and  developmental-disability biases. Nature Genetics. 2017 Apr;49(4):515-526

2Tianyun Wang#Hui Guo#Bo Xiong#Holly A.F. Stessman#Huidan WuBradley P. CoeTychele N. TurnerYanling LiuWenjing ZhaoKendra HoekzemaLaura VivesLu XiaMeina TangJianjun OuBiyuan ChenYidong ShenGuanglei XunMin LongJanice LinZev N. KronenbergYu PengTing BaiHonghui LiXiaoyan KeZhengmao HuJingping ZhaoXiaobing ZouKun Xia*, & Evan E. Eichler*,De novo genic mutations among a Chinese autism spectrum disorder cohort. Nature Communications, 2016; 7: 13316.

3Raphael Bernier#, Christelle Golzio#, Bo Xiong#, Holly A. Stessman#, Bradley P. Coe#, Osnat Penn, Kali Witherspoon, Jennifer Gerdts, Carl Baker, Anneke T. Vulto-van Silfhout, Janneke H. Schuurs-Hoeijmakers, Marco Fichera, Paolo Bosco, Serafino Buono, Antonino Alberti, Pinella Failla, Hilde Peeters, Jean Steyaert, Lisenka E.L.M. Vissers, Ludmila Francescatto, Heather C. Mefford, Jill A. Rosenfeld, Trygve Bakken, Brian J. O’Roak, Matthew Pawlus, Randall Moon, Jay Shendure, David G. Amaral, Ed Lein, Julia Rankin, Corrado Romano, Bert B.A. de Vries, Nicholas Katsanis, Evan E. Eichler. Disruptive CHD8 mutations define a subtype of autism early in development. Cell, 2014, Jul 17;158(2):263-76

4Bo Xiong, Hugo J. Bellen. Rhodopsin homeostasis and retinal degeneration: lessons from the fly. Trends in Neurosciences, 2013, 36(11):652-60

5Bo Xiong, Vafa Bayat, Manish Jaiswal, Ke Zhang, Hector Sandoval, Wu-Lin Charng, Tongchao Li, Gabriela David, Lita Duraine, Yong-Qi Lin, G. Gregory Neely, Shinya Yamamoto, Hugo J. Bellen. Crag is a GEF for Rab11 required for Rhodopsin trafficking and maintenance of adult photoreceptor cells. PLoS Biology, 2012, 10:e1001438

6Yanning Rui#, Zhen Xu#, Bo Xiong#, Ying Cao#, Shuyong Lin, Min Zhang, Siu-Chiu Chan, Wen Luo, Ying Han, Zailian Lu, Zhiyun Ye, Hai-Meng Zhou, Jiahuai Han, Anming Meng*, Sheng-Cai Lin*. A beta-catenin-independent dorsalization pathway activated by Axin/JNK signaling and antagonized by aida. Developmental Cell, 2007, 13:268-282

7Bo Xiong#, Yanning Rui#, Min Zhang, Kehui Shi, Shunji Jia, Tian Tian, Kun Yin, Huizhe Huang, Shuyong Lin, Xingang Zhao, Yinghua Chen, Ye-Guang Chen , Sheng-Cai Lin*, Anming Meng*. Tob1 controls dorsal development of zebrafish embryos by antagonizing maternal beta-catenin transcriptional activity. Developmental Cell, 2006, 11:225-238

Awards and Honors


Courses Taught

Forensic Biology

Molecular Biology of the Cell

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