On October 9,2020, four professors from Harvard University, Brown University, etc., brought a wonderful cloud academic exchange. The international exchange conference was divided into two sessions, chaired by ProfessorAihua Liao and Professor ShuiqiaoYuan.
Professor Zhibing Zhang gave a detailed introduction to SPAG6 with the theme of "SPAG6, more than a central apparatus protein, its new roles in cell growth, division, migration, ciliogenesis, and spermatogenesis", and described the mechanism of spag6 gene regulating spermatogenesis and cilia formation using spag6 mutant mouse model. Then Professor Wenfeng An described the research progress of LINE-1 with the theme of "MouseModels of LINE-1 Retrotransposons: Lessons and Insights".
That evening, Professor Surendra Sharma and Professor Tamara Tilburgs gave a wonderful speech. First, Professor Surendra Sharma brought a report entitled “Inflammatory trans-differentiation of uterine regulatory T cells programs autism-like pathology in the male offspring".He explained four questions for everyone: One is that there are no obvious Th17T cells in the uterus during normal pregnancy (producing IL-17a), How are they produced? Are checkpoint molecules involved in Tregs-Th17 differentiation?Uterine Treg-Th17 differentiation and cortical structural changes, Are transcriptional mutations in the cortex associated with autism-like behavior changes? Fourth, can Tregs consumption inhibit the occurrence of fetal neurodevelopmental defects? Professor Tamara Tilburgs gave a lecture on” The role of HLA-G+ extravillous trophoblast in tolerance and immunity at the human maternal-fetal interface", She described the phenotype and function of HLG EVT in decidual tissue of early and late pregnancy, And explored its effect on Treg cell function, The interaction between decidual NK cells and EVT cells was also introduced.
After the report, teachers and students and several professors had a heated discussion on related issues. Professors' excellent academic reports not only bring us cutting-edge scientific research progress, but also expand our related fields.