XIAO Xianjin

Author: Source: Date:October 10, 2017 Cilk Times:[]

                           

Job title: professor of Reproductive medicine

Phone: +86-83692651                                

Email: xiaoxianjin@hust.edu.cn                                

Academic Areas: Molecular Dignosis, Reproductive Medicine, Analytical Chemistry

Research Interests: Liquid biopsy, Molecular diagnostics, Nucleic acid analysis

Xianjin Xiao was born in 1989. He received his B.S. in 2011 and Ph.D in 2016 from Peking University. He was an exchange student in UC Berkeley from 2013 to 2014. Since 2016/07, he joined HUST as an associate professor, and his research interests are ctDNA based liquid biopsy for cancer dignostics. He has published over 13 papers in Nucleic Acids Research, Chemical Science and etc.

Academic Degrees

Ph. D in Analytical Chemistry, 2016. Peking University. Beijing, China;

B. A in Chemistry,2011. Peking University. Beijing, China.

Professional Experience

2013-2014, Visiting student, Department of Physics, University of California, Berkeley.

2016-2020, Associate Professor, Family Planning Research Institute, Tongji Medical College, Huazhong University of Science and Technology.

2020-Present,Professor, Institute of Reproductive Health, Tongji Medical College, Huazhong University of Science and Technology.

Selected Publications

Xianjin Xiao, Tongbo Wu, Lei Xu, Wei Chen, Meiping Zhao*, A branch-migration based fluorescent probe for straightforward, sensitive and specific discrimination of DNA mutations, Nucleic Acids Research, 2017, doi: 10.1093/nar/gkx117.(IF:10.162)

Xianjin Xiao, Tongbo Wu, Feidan Gu and Meiping Zhao*, Generation of artificial sequence specific nucleases via preassembled inert-template. Chemical Science, 2016, 7, 2051-2057 (IF:9.211)

Xianjin Xiao, Chen Zhang, Xin Su, Chen Song and Meiping Zhao*, A universal mismatch-directed signal amplification platform for ultra-selective and sensitive DNA detection under mild isothermal conditions. Chemical Science, 2012, 3, 2257–2261. (IF: 9.211)

Xianjin Xiao, Yang Liu and Meiping Zhao*, Endonuclease IV discriminates mismatches next to the apurinic/apyrimidinic site in DNA strands: Constructing DNA sensing platforms with extremely high selectivity. Chemical Communications, 2013, 49, 2819–2821. (IF: 6.834)

Xianjin Xiao, Chen Song, Chen Zhang, Xin Su and Meiping Zhao*, Ultra-selective and sensitive DNA detection by a universal apurinic/ apyrimidinic probe-based Endonuclease IV signal amplification system. Chemical Communications, 2012, 48, 1964–1966. (IF: 6.834)

Xianjin Xiao, Anqin Xu, Junqiu Zhai and Meiping Zhao*, Combination of a modified block PCR and endonuclease IV-based signal amplification system for ultra-sensitive detection of low-abundance point mutations. Methods, 2013, 64, 255–259. (IF: 3.645)

Lu Chen, Simin Fang, Xianjin Xiao*, Bo Zheng, and Meiping Zhao*, Single-Stranded DNA Assisted Cell Penetrating Peptide–DNA Conjugation Strategy for Intracellular Imaging of Nucleases. Analytical Chemistry, 2016, 88, 11306-11309.

Xin Su, Xianjin Xiao, Chen Zhang, and Meiping Zhao*, Nucleic Acid Fluorescent Probes for Biological Sensing, Applied Spectroscopy, 2012, 66, 1249–1262.

Tongbo Wu, Xianjin Xiao, Zhe Zhang and Meiping Zhao*, Enzyme-Mediated Single-Nucleotide Variation Detection at Room Temperature with High Discrimination Factor, Chemical Science, 2015, 6, 1206–1211.

Xin Su, Chen Zhang, Xianjin Xiao, Anqin Xu, Zhendong Xu and Meiping Zhao*, A kinetic method for expeditious detection of pyrophosphate anions at nanomolar concentrations based on a nucleic acid fluorescent sensor, Chemical Communications, 2013, 49, 798–800.

Meiping Zhao*, Tongbo Wu, Xianjin Xiao, Yang Liu and Xin Su, New advances in molecular recognition based on biomolecular scaffolds, Analytical and Bioanalytical Chemistry, 2013, 405, 5679–5685.

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